Stocktoria

Alector, Inc. ALEC

Nasdaq · stock · Biological Products, (No Diagnostic Substances) · website · IPO 2019-02-07 · LEI

Alector, Inc. (ALEC) earns a Piotroski F-score of 1/9 (weak financial health), with an Altman Z″ in the distress zone. It does not currently pay a dividend. FY2025 revenue was $21.0M at a -679.2% net margin.

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8/100
Stocktoria Quality Score · grade D
1/9
Piotroski F — financial health
-9.85
Altman Z″ — distress risk · distress
Dividend yield · no dividend

Quality score trend · recomputed for each fiscal year

Piotroski F /9
1 2 4 2 0 2 1 2019202020212022202320242025
Altman Z″
1.97 0.60 3.43 2.09 -0.98 -3.26 -9.85 2019202020212022202320242025

Each year's score is computed from that year's filing — a rising Piotroski F or Altman Z″ means improving financial health, a fall is worth a look.

$2.15 as of 2026-08-01 · -8.5% 1y
$1.33$2.9652-wk
Market cap USD$207M
Net margin 5y avg-209.8%
Return on equity 5y avg-146.3%
Beta0.59
Employees103

Analyst price target

$3.10 +44.2% vs last
· 5 analysts
target range $1.00 – $6.00

Wall Street analyst consensus — a sentiment gauge, not our scoring.

Revenue trend · last 8y · down

How it ranks in Manufacturing · percentile among 1957 companies

Piotroski Fstronger than 1%
Net marginstronger than 12%
Return on equitystronger than 4%
Revenue growthstronger than 2%

Percentile vs other Manufacturing companies we cover — e.g. “stronger than 90%” means only 10% score higher on that measure.

Piotroski F breakdown · 1/9 tests passed

Altman Z″ components · distress zone

ComponentValue
Working capital / assets0.672
Retained earnings / assets-3.315
EBIT / assets-0.532
Equity / liabilities0.117

Sector peers · similar-size Manufacturing companies compare side by side →

TickerCompanyPiotroski FAltman Z″P / ERevenue growth
ALECAlector, Inc.1/9-9.85-79.1%
LENZLENZ Therapeutics, Inc.2/915.45
MGXMetagenomi Therapeutics, Inc.1/9-0.61-51.8%
PTHSPelthos Therapeutics Inc.4/9-1.47
RLAYRelay Therapeutics, Inc.3/92.96+53.4%
LCTXLineage Cell Therapeutics, Inc.3/9-12.25
ELUTELUTIA INC.4/9-8.050.8-15%

All Manufacturing companies →

About Alector, Inc.

Alector, Inc., a clinical stage biotechnology company, develops therapies to counteract the progression of neurodegeneration in the United States. Its pipeline includes Nivisnebart, an investigational human recombinant monoclonal antibody for treating prevalent neurodegenerative diseases; AL137, an anti-amyloid beta antibody paired in preclinical development for the potential treatment of Alzheimer's disease; and AL050, a GCase enzyme replacement therapy in preclinical development for the potential treatment of Parkinson's disease and Lewy body dementia in patients having GBA1 gene mutations. The company also develops its preclinical and research pipeline comprising AL064, a tau siRNA for Alzheimer's disease and other tauopathies; ADP062-ABC, an alpha-synuclein siRNA for Parkinson's disease; and ADP065-ABC, an NLRP3 siRNA for neurodegenerative conditions. It has a strategic collaboration agreement with GlaxoSmithKline plc for the development and commercialization of progranulin-elevating monoclonal antibodies, including Latozinemab and Nivisnebart. The company was founded in 2013 and is headquartered in South San Francisco, California.

FAQ

Is ALEC financially healthy?

Alector, Inc.'s Piotroski F-score is 1/9 (8–9 is excellent, 0–3 weak), and its Altman Z″ distress score is in the distress zone.

Does ALEC pay a dividend?

No, Alector, Inc. does not currently pay a dividend.

How profitable is ALEC?

In FY2025, Alector, Inc. had a net margin of -679.2% and a return on equity of -466.3%.

What is the analyst price target for ALEC?

The average Wall-Street price target for Alector, Inc. is $3.10, about 44.2% above the recent price, from 5 analysts.

Is ALEC a good stock to buy?

Stocktoria doesn't give buy or sell advice, but here is the data on Alector, Inc.: a Piotroski F-score of 1/9, an Altman Z″ in the distress zone. Weigh these quality and valuation signals against your own goals.

Computed from company filings · US · as of 2025-12-31. Facts plus Stocktoria's own computed scores — not investment advice.