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ALNYLAM PHARMACEUTICALS, INC. ALNY

Nasdaq · stock · Pharmaceutical Preparations · website · IPO 2004-05-28 · LEI

ALNYLAM PHARMACEUTICALS, INC. statistics & valuation

Market cap$38.9B
P / E124.0×
P / S10.5×
P / B49.3×
P / FCF83.6×
Net margin8.4%
Return on equity39.8%
FCF margin12.5%
Return on capital14.3%
Graham number -92.2%$17.53

Market cap as of 2026-06-29. Multiples are price-derived and refreshed daily; everything else from the latest financial reports. The Graham number is Benjamin Graham's rough maximum fair value ($17.53); a green figure means the price is below it.

Profitability & efficiency

Net margin (%)
-869.60% -545.90% -1016.60% -403.20% -174.10% -101.00% -109.00% -24.10% -12.40% 8.40% 2016201720182019202020212022202320242025
Gross margin (%)
2016201720182019202020212022202320242025
Operating margin (%)
-900.30% -556.20% -1087.60% -427.50% -168.10% -83.90% -75.70% -15.40% -7.90% 13.50% 2016201720182019202020212022202320242025
Return on equity (%)
-44.60% -27.80% -58.50% -61.60% -84.50% -145.00% -414.60% 39.80% 2016201720182019202020212022202320242025
Shares outstanding
85.9M 99.7M 101.2M 112.2M 116.4M 120.2M 123.9M 125.8M 129.3M 134.7M 2016201720182019202020212022202320242025
Net debt ($)
-$305.3M -$144.3M 2016201720182019202020212022202320242025
Share buybacks ($)
2016201720182019202020212022202320242025
Return on assets (%)
-32.50% -24.60% -48.40% -37.00% -25.20% -23.40% -31.90% -11.50% -6.60% 6.30% 2016201720182019202020212022202320242025
Free cash flow margin (%)
-789.40% -541.60% -920.50% -190.50% -139.10% -85.00% -59.10% 2.30% -1.90% 12.50% 2016201720182019202020212022202320242025
Debt / equity (×)
0.19× 1.15× 2016201720182019202020212022202320242025
EPS ($)
-$8.11 -$7.46 -$7.20 -$9.30 -$3.52 -$2.18 $2.33 2016201720182019202020212022202320242025

Margins and returns computed from annual filings. Falling shares outstanding = buybacks; rising = dilution. Net debt = debt − cash (negative = net cash).

Key ratios (by fiscal year)

RatioFY2025FY2024FY2023FY2022FY2021FY2020FY2019FY2018FY2017FY2016
Operating margin13.5%-7.9%-15.4%-75.7%-83.9%-168.1%-427.5%-1087.6%-556.2%-900.3%
Net margin8.4%-12.4%-24.1%-109.0%-101.0%-174.1%-403.2%-1016.6%-545.9%-869.6%
FCF margin12.5%-1.9%2.3%-59.1%-85.0%-139.1%-190.5%-920.5%-541.6%-789.4%
Return on assets6.3%-6.6%-11.5%-31.9%-23.4%-25.2%-37.0%-48.4%-24.6%-32.5%
Return on equity39.8%-414.6%199.5%714.9%-145.0%-84.5%-61.6%-58.5%-27.8%-44.6%
Debt / equity————1.15×0.19×————
Current ratio2.762.783.083.514.044.474.876.6912.235.10

Computed from company filings · US · as of 2025-12-31. Facts plus Stocktoria's own computed scores — not investment advice.