Stocktoria

Annexon, Inc. ANNX

Nasdaq · stock · Pharmaceutical Preparations · website · IPO 2020-07-24

Annexon, Inc. (ANNX) earns a Piotroski F-score of 1/9 (weak financial health), with an Altman Z″ in the distress zone. It does not currently pay a dividend.

Chart by TradingView
13/100
Stocktoria Quality Score · grade D
1/9
Piotroski F — financial health
-7.93
Altman Z″ — distress risk · distress
Dividend yield · no dividend

Quality score trend · recomputed for each fiscal year

Piotroski F /9
3 1 1 3 2 1 202020212022202320242025
Altman Z″
3.16 1.25 1.49 1.19 -7.93 202020212022202320242025

Each year's score is computed from that year's filing — a rising Piotroski F or Altman Z″ means improving financial health, a fall is worth a look.

$5.33 as of 2026-08-01 · +158.7% 1y
$2.06$6.2452-wk
Market cap USD$898M
Return on equity 5y avg-63.2%
Beta1.18
Employees93

Analyst price target

$13.12 +146.2% vs last
· 8 analysts
target range $7.00 – $27.00

Wall Street analyst consensus — a sentiment gauge, not our scoring.

Smart money · insiders, last 12 months

Insiders net bought +$3.4M on the open market · 3 trades

Open-market insider purchases minus sells (SEC Form 4) — real buying with their own money is a bullish “smart money” signal; grants and option exercises are excluded.

How it ranks in Manufacturing · percentile among 1957 companies

Piotroski Fstronger than 1%
Return on equitystronger than 19%

Percentile vs other Manufacturing companies we cover — e.g. “stronger than 90%” means only 10% score higher on that measure.

Piotroski F breakdown · 1/9 tests passed

Altman Z″ components · distress zone

ComponentValue
Working capital / assets0.719
Retained earnings / assets-3.305
EBIT / assets-0.78
Equity / liabilities3.211

Sector peers · similar-size Manufacturing companies compare side by side →

TickerCompanyPiotroski FAltman Z″P / ERevenue growth
ANNXAnnexon, Inc.1/9-7.93
JNJJOHNSON & JOHNSON4/922.9+6%
LLYELI LILLY & Co7/955.1+44.7%
MRKMerck & Co., Inc.4/917.4+1.3%
PFEPFIZER INC4/917.8-1.6%
ABBVAbbVie Inc.7/9-0.34105.9+8.6%
BMYBRISTOL MYERS SQUIBB CO7/916.7-0.2%

All Manufacturing companies →

About Annexon, Inc.

Annexon, Inc., a clinical-stage biopharmaceutical company, discovers and develops medicines for treating inflammatory-related diseases. The company provides Tanruprubart, an investigational full-length monoclonal antibody, which is in Phase 3 clinical trial for the treatment of patients with guillain-barré syndrome; completed Phase II clinical trial for treating Huntington's disease; and in Phase 2a clinical trial for the treatment of amyotrophic lateral sclerosis. It is also developing ANX007, an antigen-binding fragment (Fab) that is in Phase 3 program for the treatment of patients with geographic atrophy; and ANX1502, a novel oral small molecule inhibitor, which is in Phase 1 clinical trials for autoimmune indications. In addition, it develops ANX009, a C1q-blocking Fab that is in Phase I clinical trial for treating patients with lupus nephritis. The company was incorporated in 2011 and is headquartered in Brisbane, California.

FAQ

Is ANNX financially healthy?

Annexon, Inc.'s Piotroski F-score is 1/9 (8–9 is excellent, 0–3 weak), and its Altman Z″ distress score is in the distress zone.

Does ANNX pay a dividend?

No, Annexon, Inc. does not currently pay a dividend.

How profitable is ANNX?

In FY2025, Annexon, Inc. had a return on equity of -97.7%.

What is the analyst price target for ANNX?

The average Wall-Street price target for Annexon, Inc. is $13.12, about 146.2% above the recent price, from 8 analysts.

Is ANNX a good stock to buy?

Stocktoria doesn't give buy or sell advice, but here is the data on Annexon, Inc.: a Piotroski F-score of 1/9, an Altman Z″ in the distress zone. Weigh these quality and valuation signals against your own goals.

Computed from company filings · US · as of 2025-12-31. Facts plus Stocktoria's own computed scores — not investment advice.