Stocktoria

aTYR PHARMA INC ATYR

Nasdaq · stock · Biological Products, (No Diagnostic Substances) · website · IPO 2015-05-07 · LEI

aTYR PHARMA INC (ATYR) earns a Piotroski F-score of 1/9 (weak financial health), with an Altman Z″ in the distress zone. It does not currently pay a dividend. FY2025 revenue was $190,000 at a -39009.5% net margin.

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9/100
Stocktoria Quality Score · grade D
1/9
Piotroski F — financial health
-19.49
Altman Z″ — distress risk · distress
Dividend yield · no dividend

Quality score trend · recomputed for each fiscal year

Piotroski F /9
2 2 3 1 4 3 2 3 0 1 2016201720182019202020212022202320242025

Each year's score is computed from that year's filing — a rising Piotroski F or Altman Z″ means improving financial health, a fall is worth a look.

$0.54 as of 2026-08-01 · -90% 1y
$0.49$5.3852-wk
Market cap USD$52M
Net margin 5y avg-20241.1%
Return on equity 5y avg-70.2%
Beta0.54
Employees58

Analyst price target

$2.86 +428.8% vs last
· 7 analysts
target range $1.00 – $7.00

Wall Street analyst consensus — a sentiment gauge, not our scoring.

Smart money · insiders, last 12 months

Insiders net bought +$43,363 on the open market · 4 trades

Open-market insider purchases minus sells (SEC Form 4) — real buying with their own money is a bullish “smart money” signal; grants and option exercises are excluded.

Revenue trend · last 7y · down

How it ranks in Manufacturing · percentile among 1957 companies

Piotroski Fstronger than 1%
Net marginstronger than 2%
Return on equitystronger than 17%

Percentile vs other Manufacturing companies we cover — e.g. “stronger than 90%” means only 10% score higher on that measure.

Piotroski F breakdown · 1/9 tests passed

Altman Z″ components · distress zone

ComponentValue
Working capital / assets0.7
Retained earnings / assets-6.518
EBIT / assets-0.835
Equity / liabilities2.644

Sector peers · similar-size Manufacturing companies compare side by side →

TickerCompanyPiotroski FAltman Z″P / ERevenue growth
ATYRaTYR PHARMA INC1/9-19.49
ZIVOZivo Bioscience, Inc.4/9
VIVSVivoSim Labs, INC.2/9
INMBInmune Bio, Inc.3/9
ENTXEntera Bio Ltd.2/9
SNTISenti Biosciences Holdings, Inc.2/9
CELZCREATIVE MEDICAL TECHNOLOGY HOLDINGS, INC.4/9-1.04

All Manufacturing companies →

About aTYR PHARMA INC

aTyr Pharma, Inc., a clinical stage biotechnology company, engages in the discovery and development of product candidates that translate tRNA synthetase biology into new therapies for fibrosis and inflammation in the United States. Its lead therapeutic candidate efzofitimod, a selective modulator of NRP2 that is in Phase 3 clinical trial for the treatment of pulmonary sarcoidosis; Phase 2 clinical trial to treat Sarcoidosis and systemic sclerosis- interstitial lung disease (ILDs); and treatment of other ILDs, such as chronic hypersensitivity pneumonitis (CHP) and connective tissue disease related ILD. The company is developing ATYR0101, a fusion protein derived from a domain of aspartyl-tRNA synthetase, which is in preclinical development for the treatment of fibrosis; and ATYR0750, a domain of alanyl-tRNA synthetase for the treatment of liver disorders. It has collaboration and license agreement with Kyorin Pharmaceutical Co., Ltd. for the development and commercialization of efzofitimod for ILDs in Japan. aTyr Pharma, Inc. was incorporated in 2005 and is headquartered in San Diego, California.

FAQ

Is ATYR financially healthy?

aTYR PHARMA INC's Piotroski F-score is 1/9 (8–9 is excellent, 0–3 weak), and its Altman Z″ distress score is in the distress zone.

Does ATYR pay a dividend?

No, aTYR PHARMA INC does not currently pay a dividend.

How profitable is ATYR?

In FY2025, aTYR PHARMA INC had a net margin of -39009.5% and a return on equity of -109.8%.

What is the analyst price target for ATYR?

The average Wall-Street price target for aTYR PHARMA INC is $2.86, about 428.8% above the recent price, from 7 analysts.

Is ATYR a good stock to buy?

Stocktoria doesn't give buy or sell advice, but here is the data on aTYR PHARMA INC: a Piotroski F-score of 1/9, an Altman Z″ in the distress zone. Weigh these quality and valuation signals against your own goals.

Computed from company filings · US · as of 2025-12-31. Facts plus Stocktoria's own computed scores — not investment advice.