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Axsome Therapeutics, Inc. AXSM

Nasdaq · stock · Pharmaceutical Preparations · website · IPO 2015-11-19 · LEI

Axsome Therapeutics, Inc. statistics & valuation

Market cap$12.4B
P / S19.5×
Net margin-28.7%
FCF margin-14.7%
Net cash$205.2M
Enterprise value USD$12.2B
Earnings yield EBIT/EV-1.4%
Return on capital-53.6%

Market cap as of 2026-06-29. Multiples are price-derived and refreshed daily; everything else from the latest financial reports.

Profitability & efficiency

Net margin (%)
-374.00% -88.40% -74.50% -28.70% 2016201720182019202020212022202320242025
Gross margin (%)
2016201720182019202020212022202320242025
Operating margin (%)
-359.30% -85.70% -72.70% -26.10% 2016201720182019202020212022202320242025
Return on equity (%)
-126.10% -173.10% -3301.50% -38.20% -90.40% -834.30% -170.80% -125.30% -503.80% -207.50% 2016201720182019202020212022202320242025
Shares outstanding
19.1M 25.5M 30.1M 36.9M 37.4M 37.8M 43.5M 47.4M 48.7M 50.9M 2016201720182019202020212022202320242025
Net debt ($)
$9.5M $6.7M $3.6M -$202.6M -$135.6M -$37.4M -$106.6M -$208.1M -$134.6M -$205.2M 2016201720182019202020212022202320242025
Share buybacks ($)
2016201720182019202020212022202320242025
Return on assets (%)
-71.20% -81.40% -201.30% -31.00% -55.30% -148.50% -56.50% -40.70% -50.50% -26.60% 2016201720182019202020212022202320242025
Free cash flow margin (%)
-234.30% -53.80% -33.40% -14.70% 2016201720182019202020212022202320242025
Debt / equity (×)
0.44× 0.40× 3.86× 0.10× 0.42× 3.14× 0.86× 0.93× 3.17× 1.33× 2016201720182019202020212022202320242025
EPS ($)
-$2.77 -$3.47 -$4.60 -$5.27 -$5.99 -$3.68 2016201720182019202020212022202320242025

Margins and returns computed from annual filings. Falling shares outstanding = buybacks; rising = dilution. Net debt = debt − cash (negative = net cash).

Key ratios (by fiscal year)

RatioFY2025FY2024FY2023FY2022FY2021FY2020FY2019FY2018FY2017FY2016
Operating margin-26.1%-72.7%-85.7%-359.3%——————
Net margin-28.7%-74.5%-88.4%-374.0%——————
FCF margin-14.7%-33.4%-53.8%-234.3%——————
Return on assets-26.6%-50.5%-40.7%-56.5%-148.5%-55.3%-31.0%-201.3%-81.4%-71.2%
Return on equity-207.5%-503.8%-125.3%-170.8%-834.3%-90.4%-38.2%-3301.5%-173.1%-126.1%
Debt / equity1.33×3.17×0.93×0.86×3.14×0.42×0.10×3.86×0.40×0.44×
Current ratio1.552.113.632.543.757.859.001.412.905.30

Computed from company filings · US · as of 2025-12-31. Facts plus Stocktoria's own computed scores — not investment advice.