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BIOCRYST PHARMACEUTICALS INC BCRX

Nasdaq · stock · Biological Products, (No Diagnostic Substances) · website · IPO 1994-03-04 · LEI

BIOCRYST PHARMACEUTICALS INC statistics & valuation

Market cap$2.5B
P / E9.6×
P / S2.9×
Net margin30.2%
Net cash$89.7M
Net debt / EBITDA-0.3×
Enterprise value USD$2.4B
EV / EBITDA7.1×
Earnings yield EBIT/EV14%
Return on capital107.2%

Market cap as of 2026-06-29. Multiples are price-derived and refreshed daily; everything else from the latest financial reports.

Profitability & efficiency

Net margin (%)
-209.30% -261.20% -490.30% -223.00% -1026.40% -117.10% -91.20% -68.40% -19.70% 30.20% 2016201720182019202020212022202320242025
Gross margin (%)
2016201720182019202020212022202320242025
Operating margin (%)
-184.40% -227.90% -456.20% -203.70% -981.10% -113.10% -54.80% -31.30% -0.60% 39.00% 2016201720182019202020212022202320242025
Return on equity (%)
-3494.60% -78.50% -205.70% -284.70% 2016201720182019202020212022202320242025
Shares outstanding
73.8M 98.4M 110.1M 154.1M 176.9M 184.3M 187.9M 205.8M 208.5M 218.6M 2016201720182019202020212022202320242025
Net debt ($)
$896000 -$27.3M $3.3M -$64.2M -$149.5M -$206.2M -$73.1M $192.6M $210.2M -$89.7M 2016201720182019202020212022202320242025
Share buybacks ($)
2016201720182019202020212022202320242025
Return on assets (%)
-61.40% -36.90% -69.00% -62.10% -54.60% -31.30% -44.90% -43.80% -18.10% 51.30% 2016201720182019202020212022202320242025
Free cash flow margin (%)
-164.70% -450.00% -184.10% 2016201720182019202020212022202320242025
Debt / equity (×)
14.58× 0.27× 0.61× 1.31× 2016201720182019202020212022202320242025
EPS ($)
-$1.09 -$1.03 -$1.33 -$1.18 -$0.43 $1.21 2016201720182019202020212022202320242025

Margins and returns computed from annual filings. Falling shares outstanding = buybacks; rising = dilution. Net debt = debt − cash (negative = net cash).

Key ratios (by fiscal year)

RatioFY2025FY2024FY2023FY2022FY2021FY2020FY2019FY2018FY2017FY2016
Operating margin39.0%-0.6%-31.3%-54.8%-113.1%-981.1%-203.7%-456.2%-227.9%-184.4%
Net margin30.2%-19.7%-68.4%-91.2%-117.1%-1026.4%-223.0%-490.3%-261.2%-209.3%
FCF margin——————-184.1%-450.0%-164.7%—
Return on assets51.3%-18.1%-43.8%-44.9%-31.3%-54.6%-62.1%-69.0%-36.9%-61.4%
Return on equity-221.4%18.7%49.7%83.9%172.0%949.1%-284.7%-205.7%-78.5%-3494.6%
Debt / equity-0.00×-0.66×-0.67×-0.79×-2.79×-6.37×1.31×0.61×0.27×14.58×
Current ratio2.062.633.314.905.463.061.781.651.681.23

Computed from company filings · US · as of 2025-12-31. Facts plus Stocktoria's own computed scores — not investment advice.