Stocktoria

BICYCLE THERAPEUTICS PLC BCYC

Nasdaq · stock · Pharmaceutical Preparations · website · IPO 2019-05-23 · LEI

BICYCLE THERAPEUTICS PLC (BCYC) earns a Piotroski F-score of 1/9 (weak financial health), with an Altman Z″ in the safe zone. It does not currently pay a dividend. FY2025 revenue was $72.6M at a -301.7% net margin.

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44/100
Stocktoria Quality Score · grade C
1/9
Piotroski F — financial health
5.27
Altman Z″ — distress risk · safe
Dividend yield · no dividend

Quality score trend · recomputed for each fiscal year

Piotroski F /9
3 1 4 2 4 3 1 2019202020212022202320242025
Altman Z″
6.85 1.69 6.09 2.54 2.21 7.20 5.27 2019202020212022202320242025

Each year's score is computed from that year's filing — a rising Piotroski F or Altman Z″ means improving financial health, a fall is worth a look.

$4.06 as of 2026-08-01 · -45% 1y
$3.86$8.0752-wk
Market cap USD$286M
Net margin 5y avg-560.2%
Return on equity 5y avg-33.4%
Beta1.54
Employees288

Analyst price target

$12.62 +211% vs last
consensus: buy · 8 analysts
target range $5.00 – $36.00

Wall Street analyst consensus — a sentiment gauge, not our scoring.

Revenue trend · last 8y · up

How it ranks in Manufacturing · percentile among 1957 companies

Piotroski Fstronger than 1%
Net marginstronger than 16%
Return on equitystronger than 34%
Revenue growthstronger than 97%

Percentile vs other Manufacturing companies we cover — e.g. “stronger than 90%” means only 10% score higher on that measure.

Piotroski F breakdown · 1/9 tests passed

Altman Z″ components · safe zone

ComponentValue
Working capital / assets0.872
Retained earnings / assets-1.254
EBIT / assets-0.344
Equity / liabilities5.668

Sector peers · similar-size Manufacturing companies compare side by side →

TickerCompanyPiotroski FAltman Z″P / ERevenue growth
BCYCBICYCLE THERAPEUTICS PLC1/95.27+105.8%
ASMBASSEMBLY BIOSCIENCES, INC.3/9-1.34+153.5%
VRDNViridian Therapeutics, Inc.DE2/92.72
ABCLAbCellera Biologics Inc.4/94.67+160.6%
RMTIROCKWELL MEDICAL, INC.2/9-18.33-31.8%
CTMXCytomX Therapeutics, Inc.1/9-10.12-44.8%
KURAKura Oncology, Inc.2/9-2.37+25.2%

All Manufacturing companies →

About BICYCLE THERAPEUTICS PLC

Bicycle Therapeutics plc, a clinical-stage pharmaceutical company, develops a class of medicines for diseases that are underserved by existing therapeutics in the United States and the United Kingdom. The company's products pipeline include zelenectide pevedotin, a bicycle toxin conjugate (BTC), which is in phase II clinical trials for the treatment of high nectin-4 expressing tumors; nuzefatide pevedotin (EphA2), a BTC that is in phase I/II clinical trials to treat Ephrin type A receptor 2 expressing tumor; BT7480, a Bicycle tumor-targeted immune cell agonist molecule, which is in phase I/II targeting nectin-4 and agonizing CD137; and BT1702, a theranostic BRC molecule targeting MT1-MMP for which IND-enabling activities are ongoing. In addition, it develops Novel CNS targets, which is in preclinical trial targeting CNS disease; Novel neuromuscular targets, which is in preclinical trial targeting neuromuscular disease; and programs that are in preclinical trial targeting radiopharmaceutical. Further, the company collaborates with biopharmaceutical companies and organizations to develop programs in therapeutic areas. It has collaboration and license agreement with Bayer Consumer Care AG; Novartis Pharma AG; Ionis Pharmaceuticals, Inc.; Genentech, Inc; and AstraZeneca AB. Bicycle Therapeutics plc was incorporated in 2009 and is headquartered in Cambridge, the United Kingdom.

FAQ

Is BCYC financially healthy?

BICYCLE THERAPEUTICS PLC's Piotroski F-score is 1/9 (8–9 is excellent, 0–3 weak), and its Altman Z″ distress score is in the safe zone.

Does BCYC pay a dividend?

No, BICYCLE THERAPEUTICS PLC does not currently pay a dividend.

How profitable is BCYC?

In FY2025, BICYCLE THERAPEUTICS PLC had a net margin of -301.7% and a return on equity of -35.9%.

What is the analyst price target for BCYC?

The average Wall-Street price target for BICYCLE THERAPEUTICS PLC is $12.62, about 211.0% above the recent price, from 8 analysts (consensus: buy).

Is BCYC a good stock to buy?

Stocktoria doesn't give buy or sell advice, but here is the data on BICYCLE THERAPEUTICS PLC: a Piotroski F-score of 1/9, an Altman Z″ in the safe zone. Weigh these quality and valuation signals against your own goals.

Computed from company filings · US · as of 2025-12-31. Facts plus Stocktoria's own computed scores — not investment advice.