Stocktoria

CRESCENT BIOPHARMA, INC. CBIO

Nasdaq · stock · Pharmaceutical Preparations · website · IPO 2014-01-10

CRESCENT BIOPHARMA, INC. (CBIO) earns a Piotroski F-score of 4/9 (mixed financial health), with an Altman Z″ in the safe zone. It does not currently pay a dividend. FY2025 revenue was $10.8M at a -1419.6% net margin.

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48/100
Stocktoria Quality Score · grade C
4/9
Piotroski F — financial health
4.59
Altman Z″ — distress risk · safe
Dividend yield · no dividend

Quality score trend · recomputed for each fiscal year

Piotroski F /9
2 3 3 1 1 1 1 3 1 4 2016201720182019202020212022202320242025
Altman Z″
-3.69 14.59 10.21 5.51 -5.19 -4.90 4.59 2016201720182019202020212022202320242025

Each year's score is computed from that year's filing — a rising Piotroski F or Altman Z″ means improving financial health, a fall is worth a look.

$16.43 as of 2026-08-01 · +14.1% 1y
$9.59$22.3752-wk
Market cap USD$512M
Net margin 5y avg-109533.6%
Return on equity 5y avg-89.6%
Employees55

Analyst price target

$31.00 +88.7% vs last
consensus: strong buy · 5 analysts
target range $27.00 – $35.00

Wall Street analyst consensus — a sentiment gauge, not our scoring.

Smart money · insiders, last 12 months

Insiders net sold -$1.2M on the open market · 7 trades

Open-market insider purchases minus sells (SEC Form 4) — real buying with their own money is a bullish “smart money” signal; grants and option exercises are excluded.

Revenue trend · last 6y · up

How it ranks in Manufacturing · percentile among 1957 companies

Piotroski Fstronger than 45%
Net marginstronger than 9%
Return on equitystronger than 22%

Percentile vs other Manufacturing companies we cover — e.g. “stronger than 90%” means only 10% score higher on that measure.

Piotroski F breakdown · 4/9 tests passed

Altman Z″ components · safe zone

ComponentValue
Working capital / assets0.835
Retained earnings / assets-0.715
EBIT / assets-0.635
Equity / liabilities5.445

Sector peers · similar-size Manufacturing companies compare side by side →

TickerCompanyPiotroski FAltman Z″P / ERevenue growth
CBIOCRESCENT BIOPHARMA, INC.4/94.59
JAGXJaguar Health, Inc.2/9-1.5%
JANXJanux Therapeutics, Inc.2/9-5.6%
PRTAPROTHENA CORP PUBLIC LTD CO1/9-5.98-92.8%
PGENPRECIGEN, INC.2/9
PRLDPrelude Therapeutics Inc3/9-17.29
EVMNEvommune, Inc.2/99.47

All Manufacturing companies →

About CRESCENT BIOPHARMA, INC.

Crescent Biopharma, Inc., a biotechnology company, researches and develops cancer therapy candidates in the United States. Its pipeline includes CR-001, which is in Phase 3 clinical trial, a proprietary anti-PD-1/anti-VEGF bispecific antibody to treat solid tumors; and CR-002, and CR-003. The company has a strategic partnership with Sichuan Kelun-Biotech Biopharmaceutical Co., Ltd. for the development and commercialization of oncology therapeutics. The company was formerly known as GlycoMimetics, Inc. The company was founded in 2024 and is headquartered in Waltham, Massachusetts.

FAQ

Is CBIO financially healthy?

CRESCENT BIOPHARMA, INC.'s Piotroski F-score is 4/9 (8–9 is excellent, 0–3 weak), and its Altman Z″ distress score is in the safe zone.

Does CBIO pay a dividend?

No, CRESCENT BIOPHARMA, INC. does not currently pay a dividend.

How profitable is CBIO?

In FY2025, CRESCENT BIOPHARMA, INC. had a net margin of -1419.6% and a return on equity of -75.8%.

What is the analyst price target for CBIO?

The average Wall-Street price target for CRESCENT BIOPHARMA, INC. is $31.00, about 88.7% above the recent price, from 5 analysts (consensus: strong buy).

Is CBIO a good stock to buy?

Stocktoria doesn't give buy or sell advice, but here is the data on CRESCENT BIOPHARMA, INC.: a Piotroski F-score of 4/9, an Altman Z″ in the safe zone. Weigh these quality and valuation signals against your own goals.

Computed from company filings · US · as of 2025-12-31. Facts plus Stocktoria's own computed scores — not investment advice.