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CRISPR Therapeutics AG CRSP

Nasdaq · stock · Biological Products, (No Diagnostic Substances) · website · IPO 2016-10-19 · LEI

CRISPR Therapeutics AG statistics & valuation

Market cap$5.3B
P / B2.8×
Net margin-16569.8%
Return on equity-30.3%
FCF margin-9855.5%
Net cash$347.6M
Enterprise value USD$4.9B
Earnings yield EBIT/EV-13.4%
Return on capital-31.4%

Market cap as of 2026-06-29. Multiples are price-derived and refreshed daily; everything else from the latest financial reports.

Profitability & efficiency

Net margin (%)
-448.80% -166.70% -5281.10% 23.10% -48520.90% 41.30% -54271.70% -41.40% -981.50% -16569.80% 2016201720182019202020212022202320242025
Gross margin (%)
2016201720182019202020212022202320242025
Operating margin (%)
-1319.30% -157.70% -5087.80% 16.10% -49295.50% 40.80% -56190.40% -60.00% -1250.40% -18933.60% 2016201720182019202020212022202320242025
Return on equity (%)
-10.00% -36.40% -42.10% 7.10% -21.00% 15.70% -34.70% -8.20% -19.00% -30.30% 2016201720182019202020212022202320242025
Shares outstanding
39.7M 40.6M 51.9M 60.8M 73.9M 80.4M 78.5M 80.0M 85.7M 95.9M 2016201720182019202020212022202320242025
Net debt ($)
-$347.6M 2016201720182019202020212022202320242025
Share buybacks ($)
2016201720182019202020212022202320242025
Return on assets (%)
-6.70% -25.20% -33.70% 6.30% -19.10% 13.70% -29.00% -6.90% -16.30% -25.70% 2016201720182019202020212022202320242025
Free cash flow margin (%)
-1129.50% -190.00% -3169.40% 17.30% -35705.70% 50.00% -44484.90% -72.70% -387.70% -9855.50% 2016201720182019202020212022202320242025
Debt / equity (×)
0.00× 2016201720182019202020212022202320242025
EPS ($)
-$1.71 -$3.44 $1.17 -$5.29 $4.70 -$8.36 -$1.94 -$4.34 -$6.47 2016201720182019202020212022202320242025

Margins and returns computed from annual filings. Falling shares outstanding = buybacks; rising = dilution. Net debt = debt − cash (negative = net cash).

Key ratios (by fiscal year)

RatioFY2025FY2024FY2023FY2022FY2021FY2020FY2019FY2018FY2017FY2016
Operating margin-18933.6%-1250.4%-60.0%-56190.4%40.8%-49295.5%16.1%-5087.8%-157.7%-1319.3%
Net margin-16569.8%-981.5%-41.4%-54271.7%41.3%-48520.9%23.1%-5281.1%-166.7%-448.8%
FCF margin-9855.5%-387.7%-72.7%-44484.9%50.0%-35705.7%17.3%-3169.4%-190.0%-1129.5%
Return on assets-25.7%-16.3%-6.9%-29.0%13.7%-19.1%6.3%-33.7%-25.2%-6.7%
Return on equity-30.3%-19.0%-8.2%-34.7%15.7%-21.0%7.1%-42.1%-36.4%-10.0%
Debt / equity0.00×—————————
Current ratio13.3222.0717.5415.3020.1718.2117.2916.8117.1214.56

Computed from company filings · US · as of 2025-12-31. Facts plus Stocktoria's own computed scores — not investment advice.