Stocktoria

CytomX Therapeutics, Inc. CTMX

Nasdaq · stock · Pharmaceutical Preparations · website · IPO 2015-10-08 · LEI

CytomX Therapeutics, Inc. (CTMX) earns a Piotroski F-score of 1/9 (weak financial health), with an Altman Z″ in the distress zone. It does not currently pay a dividend. FY2025 revenue was $76.2M at a -22.8% net margin.

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8/100
Stocktoria Quality Score · grade D
1/9
Piotroski F — financial health
-10.12
Altman Z″ — distress risk · distress
Dividend yield · no dividend

Quality score trend · recomputed for each fiscal year

Piotroski F /9
2 5 1 1 4 1 1 2 4 1 2016201720182019202020212022202320242025
Altman Z″
0.80 3.04 2.02 -1.80 -0.95 -3.80 -9.78 -11.22 -16.14 -10.12 2016201720182019202020212022202320242025

Each year's score is computed from that year's filing — a rising Piotroski F or Altman Z″ means improving financial health, a fall is worth a look.

$3.49 as of 2026-08-01 · +71.1% 1y
$2.04$5.6952-wk
Market cap USD$740M
Net margin 5y avg-99.5%
Return on equity 5y avg-17.5%
Beta2.09
Employees69

Analyst price target

$12.50 +258.2% vs last
· 8 analysts
target range $6.00 – $16.00

Wall Street analyst consensus — a sentiment gauge, not our scoring.

Smart money · insiders, last 12 months

Insiders net sold -$905,766 on the open market · 3 trades

Open-market insider purchases minus sells (SEC Form 4) — real buying with their own money is a bullish “smart money” signal; grants and option exercises are excluded.

Revenue trend · last 10y · up

How it ranks in Manufacturing · percentile among 1957 companies

Piotroski Fstronger than 1%
Net marginstronger than 35%
Return on equitystronger than 44%
Revenue growthstronger than 4%

Percentile vs other Manufacturing companies we cover — e.g. “stronger than 90%” means only 10% score higher on that measure.

Piotroski F breakdown · 1/9 tests passed

Altman Z″ components · distress zone

ComponentValue
Working capital / assets0.642
Retained earnings / assets-4.697
EBIT / assets-0.148
Equity / liabilities1.884

Sector peers · similar-size Manufacturing companies compare side by side →

TickerCompanyPiotroski FAltman Z″P / ERevenue growth
CTMXCytomX Therapeutics, Inc.1/9-10.12-44.8%
ABCLAbCellera Biologics Inc.4/94.67+160.6%
BCYCBICYCLE THERAPEUTICS PLC1/95.27+105.8%
ETONEton Pharmaceuticals, Inc.5/9-2.05+104.9%
ASMBASSEMBLY BIOSCIENCES, INC.3/9-1.34+153.5%
VRDNViridian Therapeutics, Inc.DE2/92.72
ARCTArcturus Therapeutics Holdings Inc.1/90.81-46.1%

All Manufacturing companies →

About CytomX Therapeutics, Inc.

CytomX Therapeutics, Inc. operates as an oncology-focused biopharmaceutical company that focuses on developing potent biologics designed to treat tumor microenvironment. The company utilizes conditional activation platform technology for oncology biologics research and development comprising the validation of targets for antibody-drug conjugates (ADCs), opening therapeutic window for novel T-cell engagers (TCEs) targeting solid tumors, and increasing the therapeutic index for immune modulators, such as cytokines; and PROBODY platform in preclinical research in areas outside of oncology. It also develops CX-904, a T-cell engaging bispecific antibody targeting the epidermal growth factor receptor (EGFR) on tumor cells and the CD3 receptor on T cells; CX-2051, a conditionally activated ADC for optimizing the therapeutic index for EpCAM-expressing epithelial cancers, including colorectal cancer; and CX-801, an interferon alpha-2b PROBODY cytokine. In addition, the company's development pipeline comprises CX-2029, a conditional activated ADC targeting CD71; and BMS-986288, a PROBODY version of non-fucosylated ipilimumab. It has strategic collaborations with Amgen, Astellas, Bristol Myers Squibb, Regeneron, and Moderna; and clinical trial collaboration and supply agreement with Merck for the evaluation of CX-801 in combination with anti-PD-1 therapy, KEYTRUDA (pembrolizumab). The company was founded in 2008 and is based in South San Francisco, California.

FAQ

Is CTMX financially healthy?

CytomX Therapeutics, Inc.'s Piotroski F-score is 1/9 (8–9 is excellent, 0–3 weak), and its Altman Z″ distress score is in the distress zone.

Does CTMX pay a dividend?

No, CytomX Therapeutics, Inc. does not currently pay a dividend.

How profitable is CTMX?

In FY2025, CytomX Therapeutics, Inc. had a net margin of -22.8% and a return on equity of -17.5%.

What is the analyst price target for CTMX?

The average Wall-Street price target for CytomX Therapeutics, Inc. is $12.50, about 258.2% above the recent price, from 8 analysts.

Is CTMX a good stock to buy?

Stocktoria doesn't give buy or sell advice, but here is the data on CytomX Therapeutics, Inc.: a Piotroski F-score of 1/9, an Altman Z″ in the distress zone. Weigh these quality and valuation signals against your own goals.

Computed from company filings · US · as of 2025-12-31. Facts plus Stocktoria's own computed scores — not investment advice.