Stocktoria

Cyclerion Therapeutics, Inc. CYCN

Nasdaq · stock · Pharmaceutical Preparations · website · IPO 2019-03-18

Cyclerion Therapeutics, Inc. (CYCN) earns a Piotroski F-score of 1/9 (weak financial health). It does not currently pay a dividend. FY2025 revenue was $2.1M at a -170.1% net margin.

Chart by TradingView
6/100
Stocktoria Quality Score · grade D
1/9
Piotroski F — financial health
Altman Z″ — distress risk
Dividend yield · no dividend

Quality score trend · recomputed for each fiscal year

Piotroski F /9
3 1 3 2 2 3 1 2019202020212022202320242025

Each year's score is computed from that year's filing — a rising Piotroski F or Altman Z″ means improving financial health, a fall is worth a look.

$3.92 as of 2026-08-01 · +58.7% 1y
$1.27$3.9252-wk
Market cap USD$15M
Net margin 5y avg-4118.6%
Return on equity 5y avg-129.7%
Beta1.77
Employees1

Analyst price target

$8.00 +104.1% vs last
· 1 analysts
target range $8.00 – $8.00

Wall Street analyst consensus — a sentiment gauge, not our scoring.

Revenue trend · last 7y · down

How it ranks in Manufacturing · percentile among 1957 companies

Piotroski Fstronger than 1%
Net marginstronger than 20%
Return on equitystronger than 32%

Percentile vs other Manufacturing companies we cover — e.g. “stronger than 90%” means only 10% score higher on that measure.

Piotroski F breakdown · 1/9 tests passed

Sector peers · similar-size Manufacturing companies compare side by side →

TickerCompanyPiotroski FAltman Z″P / ERevenue growth
CYCNCyclerion Therapeutics, Inc.1/9
DNTHDianthus Therapeutics, Inc. /DE/1/914.17
ORMPORAMED PHARMACEUTICALS INC.2/97.83
LPCNLipocine Inc.-82.3%
BIOEBio Essence Corp9/914.1
CLSDQClearside Biomedical, Inc.2/9
GOVXGeoVax Labs, Inc.1/9

All Manufacturing companies →

About Cyclerion Therapeutics, Inc.

Cyclerion Therapeutics, Inc., a biopharmaceutical company, engages in the development of treatments for serious diseases serious diseases with novel sGC stimulators in both the central nervous system (CNS) and the periphery. The company is developing Olinciguat, an orally administered vascular soluble guanylate cyclase (sGC) stimulator, which is in Phase 2 clinical trial to treat cardiovascular diseases; and Praliciguat, a systemic sGC stimulator for the treatment of rare kidney disease. It has a license agreement with Akebia to develop, manufacture, medical affair, and commercializes Praliciguat and other related products. The company was incorporated in 2018 and is headquartered in Cambridge, Massachusetts.

FAQ

Is CYCN financially healthy?

Cyclerion Therapeutics, Inc.'s Piotroski F-score is 1/9 (8–9 is excellent, 0–3 weak).

Does CYCN pay a dividend?

No, Cyclerion Therapeutics, Inc. does not currently pay a dividend.

How profitable is CYCN?

In FY2025, Cyclerion Therapeutics, Inc. had a net margin of -170.1% and a return on equity of -38.8%.

What is the analyst price target for CYCN?

The average Wall-Street price target for Cyclerion Therapeutics, Inc. is $8.00, about 104.1% above the recent price, from 1 analysts.

Is CYCN a good stock to buy?

Stocktoria doesn't give buy or sell advice, but here is the data on Cyclerion Therapeutics, Inc.: a Piotroski F-score of 1/9. Weigh these quality and valuation signals against your own goals.

Computed from company filings · US · as of 2025-12-31. Facts plus Stocktoria's own computed scores — not investment advice.