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IONIS PHARMACEUTICALS INC IONS

Nasdaq · stock · Pharmaceutical Preparations · website · IPO 1991-05-17 · LEI

IONIS PHARMACEUTICALS INC financials (annual)

Revenue
$372.8M $514.2M $599.7M $1.12B $729.3M $810.5M $587.4M $787.6M $705.1M $943.7M 2016201720182019202020212022202320242025
Net income
-$60.4M $346000 $273.7M $278.1M -$444.3M -$28.6M -$269.7M -$366.3M -$453.9M -$381.4M 2016201720182019202020212022202320242025
Free cash flow
-$119.2M $139.4M $589.3M $314.7M $772000 $18.8M -$290.1M -$331.3M -$546.2M -$320.0M 2016201720182019202020212022202320242025

Bars are annual figures from 2016 to 2025; red bars are negative (a loss or cash outflow).

MetricFY2025FY2024FY2023FY2022FY2021FY2020FY2019FY2018FY2017FY2016
Revenue$943.7M$705.1M$787.6M$587.4M$810.5M$729.3M$1.1B$599.7M$514.2M$372.8M
R&D expense$915.6M$901.5M$899.6M$638.2M$531.0M$461.5M$411.9M$372.5M$340.4M
SG&A expense$393.9M$267.5M$232.6M$150.3M$186.3M$354.3M$286.6M$244.6M$108.5M$48.6M
Operating income-$381.7M-$475.1M-$353.7M-$410.2M-$30.2M-$172.1M$365.9M-$61.4M$31.0M-$20.2M
Interest expense$17.3M$17.0M$12.7M$8.1M$9.3M$9.5M$12.4M$44.8M$44.8M$38.8M
Income tax$1.8M-$6.2M$32.3M$11.7M-$551,000$345.2M$51.5M-$291.1M-$6.0M$2.9M
Net income-$381.4M-$453.9M-$366.3M-$269.7M-$28.6M-$444.3M$278.1M$273.7M$346,000-$60.4M
EPS (diluted)$-2.38$-3.04$-2.56$-1.90$-0.20$-3.18$1.90$2.07$0.15$-0.50
Operating cash flow-$268.6M-$500.9M-$307.5M-$274.4M$30.8M$35.9M$345.6M$602.9M$174.1M-$112.1M
Free cash flow-$320.0M-$546.2M-$331.3M-$290.1M$18.8M$772,000$314.7M$589.3M$139.4M-$119.2M
Cash & equivalents$372.3M$242.1M$399.3M$276.5M$869.2M$397.7M$683.3M$278.8M$129.6M$84.7M
Inventory$10.0M$12.5M$7.4M$22.0M$24.8M$22.0M$18.2M$8.6M$10.0M
Total assets$3.5B$3.0B$3.0B$2.5B$2.6B$2.4B$3.2B$2.7B$1.3B$912.5M
Total liabilities$3.0B$2.4B$2.6B$2.0B$1.8B$1.6B$1.5B$1.5B$957.5M$812.9M
Shareholders' equity$489.1M$588.4M$386.7M$572.9M$771.7M$743.3M$1.6B$1.1B$365.3M$99.6M

Growth · year-over-year · Revenue CAGR 10.9%

MetricFY2025FY2024FY2023FY2022FY2021FY2020FY2019FY2018FY2017FY2016
Revenue growth+33.8%-10.5%+34.1%-27.5%+11.1%-35.0%+87.2%+16.6%+37.9%+31.4%
Net income growth-259.7%+1.6%+79015.9%
EPS growth-267.4%-8.2%+1280.0%
Free cash flow growth-1639.4%+2340.9%-99.8%-46.6%+322.8%-987.5%

Each column is the change versus the prior fiscal year. Growth off a negative or zero base is shown as “—”. CAGR is the compound annual revenue growth across the years shown.

Computed from company filings · US · as of 2025-12-31. Facts plus Stocktoria's own computed scores — not investment advice.