Stocktoria

Opus Genetics, Inc. IRD

Nasdaq · stock · Pharmaceutical Preparations · website · IPO 2004-11-30

Opus Genetics, Inc. (IRD) earns a Piotroski F-score of 3/9 (weak financial health), with an Altman Z″ in the distress zone. It does not currently pay a dividend. FY2025 revenue was $14.2M at a -349.3% net margin.

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30/100
Stocktoria Quality Score · grade D
3/9
Piotroski F — financial health
-11.42
Altman Z″ — distress risk · distress
Dividend yield · no dividend

Quality score trend · recomputed for each fiscal year

Piotroski F /9
2 1 1 2 3 3 5 1 1 3 2016201720182019202020212022202320242025
Altman Z″
-8.69 -5.38 12.79 -18.48 -11.42 2016201720182019202020212022202320242025

Each year's score is computed from that year's filing — a rising Piotroski F or Altman Z″ means improving financial health, a fall is worth a look.

$3.76 as of 2026-08-01 · +208.2% 1y
$1.22$5.1152-wk
Market cap USD$330M
Net margin 5y avg-2101.1%
Return on equity 5y avg-283%
Beta0.55
Employees27

Analyst price target

$10.56 +180.7% vs last
consensus: strong buy · 18 analysts
target range $8.00 – $16.00

Wall Street analyst consensus — a sentiment gauge, not our scoring.

Smart money · insiders, last 12 months

Insiders net sold -$7.6M on the open market · 7 trades

Open-market insider purchases minus sells (SEC Form 4) — real buying with their own money is a bullish “smart money” signal; grants and option exercises are excluded.

Revenue trend · last 7y · up

How it ranks in Manufacturing · percentile among 1957 companies

Piotroski Fstronger than 27%
Net marginstronger than 15%
Return on equitystronger than 6%
Revenue growthstronger than 86%

Percentile vs other Manufacturing companies we cover — e.g. “stronger than 90%” means only 10% score higher on that measure.

Piotroski F breakdown · 3/9 tests passed

Altman Z″ components · distress zone

ComponentValue
Working capital / assets0.841
Retained earnings / assets-3.754
EBIT / assets-0.768
Equity / liabilities0.44

Sector peers · similar-size Manufacturing companies compare side by side →

TickerCompanyPiotroski FAltman Z″P / ERevenue growth
IRDOpus Genetics, Inc.3/9-11.42+29.1%
ABUSArbutus Biopharma Corp3/9
PYXSPyxis Oncology, Inc.2/9-16.86-14.2%
CNTACentessa Pharmaceuticals plc4/9-1.11
TNXPTonix Pharmaceuticals Holding Corp.3/9-0.37+29.8%
EVMNEvommune, Inc.2/99.47
NEUPNeuphoria Therapeutics Inc.4/9-16.04

All Manufacturing companies →

About Opus Genetics, Inc.

Opus Genetics, Inc., a clinical-stage biopharmaceutical company, develops gene therapies to restore vision and prevent blindness in patients with inherited retinal diseases (IRDs) and other types of therapies for additional ophthalmic disorders. It develops OPGx-LCA5, an early-onset retinal degeneration that is in Phase 1/2 clinical trial for the treatment of LCA5-associated IRD; and OPGx-BEST1 to treat BEST1-associated retinal disease. The company also develops various pre-clinical IRD programs, including OPGx-RHO, a gene therapy that targets autosomal dominant retinitis pigmentosa caused by RHO mutations; OPGx-RDH12 that is designed to restore protein expression and halt functional deterioration in patients with retinal dystrophy caused by mutations in the retinal dehydrogenase gene; OPGx-MERTK, an AAV vector for the treatment of MERTK IRD; OPGx-NMNAT1, a gene augmentation therapy designed to halt functional deterioration in pediatric patients with retinal degenerative disease caused by mutations in the nicotinamide mononucleotide adenylyltransferase 1 gene; and OPGx-CNGB1, an AAV gene therapy for retinitis pigmentosa due to mutations in the CNGB1 gene. In addition, it develops Phentolamine Ophthalmic Solution for reversal of mydriasis, as well as for the treatment of presbyopia and dim light or night vision disturbances and APX3330, a small-molecule inhibitor of Ref-1 for the treatment of diabetic retinopathy. Opus Genetics, Inc. was formerly known as Ocuphire Pharma, Inc. and changed its name to Opus Genetics, Inc. in November 2020. The company was founded in 2018 and is headquartered in Durham, North Carolina.

FAQ

Is IRD financially healthy?

Opus Genetics, Inc.'s Piotroski F-score is 3/9 (8–9 is excellent, 0–3 weak), and its Altman Z″ distress score is in the distress zone.

Does IRD pay a dividend?

No, Opus Genetics, Inc. does not currently pay a dividend.

How profitable is IRD?

In FY2025, Opus Genetics, Inc. had a net margin of -349.3% and a return on equity of -323.1%.

What is the analyst price target for IRD?

The average Wall-Street price target for Opus Genetics, Inc. is $10.56, about 180.7% above the recent price, from 18 analysts (consensus: strong buy).

Is IRD a good stock to buy?

Stocktoria doesn't give buy or sell advice, but here is the data on Opus Genetics, Inc.: a Piotroski F-score of 3/9, an Altman Z″ in the distress zone. Weigh these quality and valuation signals against your own goals.

Computed from company filings · US · as of 2025-12-31. Facts plus Stocktoria's own computed scores — not investment advice.