Stocktoria

LEXICON PHARMACEUTICALS, INC. LXRX

Nasdaq · stock · Pharmaceutical Preparations · website · IPO 2000-04-07

LEXICON PHARMACEUTICALS, INC. (LXRX) earns a Piotroski F-score of 3/9 (weak financial health). It does not currently pay a dividend. FY2025 revenue was $49.8M at a -101.1% net margin.

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36/100
Stocktoria Quality Score · grade D
3/9
Piotroski F — financial health
Altman Z″ — distress risk
Dividend yield · no dividend
-1.2
Beneish M-score — earnings quality · elevated

Quality score trend · recomputed for each fiscal year

Piotroski F /9
0 2 2 6 2 2 3 2 4 3 2016201720182019202020212022202320242025
Altman Z″
-7.15 -8.76 -16.26 -3.51 -16.94 2016201720182019202020212022202320242025

Each year's score is computed from that year's filing — a rising Piotroski F or Altman Z″ means improving financial health, a fall is worth a look.

$2.35 as of 2026-08-01 · +113.6% 1y
$1.10$2.4052-wk

Beneish M-score: -1.2 — elevated (above the −1.78 line — aggressive-accounting signals worth a closer look) . A statistical screen for earnings manipulation, not proof — and it doesn't apply to most banks/insurers.

Market cap USD$1.1B
Net margin 5y avg-23649.4%
Return on equity 5y avg-107.7%
Beta1.07
Employees81

Analyst price target

$3.77 +60.4% vs last
consensus: buy · 5 analysts
target range $1.75 – $6.00

Wall Street analyst consensus — a sentiment gauge, not our scoring.

Revenue trend · last 10y · down

How it ranks in Manufacturing · percentile among 1957 companies

Piotroski Fstronger than 27%
Net marginstronger than 22%
Return on equitystronger than 30%
Revenue growthstronger than 94%

Percentile vs other Manufacturing companies we cover — e.g. “stronger than 90%” means only 10% score higher on that measure.

Piotroski F breakdown · 3/9 tests passed

Sector peers · similar-size Manufacturing companies compare side by side →

TickerCompanyPiotroski FAltman Z″P / ERevenue growth
LXRXLEXICON PHARMACEUTICALS, INC.3/9+60.2%
GOSSGossamer Bio, Inc.-57.7%
OCULOCULAR THERAPEUTIX, INC3/93.49-18.5%
XOMAXOMA Royalty Corp5/9-11.8223.3+83.1%
PTGXProtagonist Therapeutics, Inc4/913.41-89.4%
SEPNSepterna, Inc.4/93.75
QTTBQ32 Bio Inc.3/9-2.117.5

All Manufacturing companies →

About LEXICON PHARMACEUTICALS, INC.

Lexicon Pharmaceuticals, Inc., a biopharmaceutical company, focuses on the discovery, development, and commercialization of pharmaceutical products for the treatment of human disease. The company develops sotagliflozin, an orally-delivered small molecule drug for the treatment of hypertrophic cardiomyopathy, and ZYNQUISTA (sotagliflozin) for the treatment of type 1 diabetes. It also commercializes INPEFA (sotagliflozin), a once-daily oral tablet to reduce the risk of cardiovascular death, hospitalization for heart failure, and urgent heart failure visit in adults with heart failure or type 2 diabetes, CKD, and other cardiovascular risk factors. In addition, the company develops LX9851, an orally-delivered small molecule drug candidate for the treatment of obesity and associated cardiometabolic disorders, and pilavapadin (LX9211), an orally-delivered small molecule drug candidate for the treatment of neuropathic pain. It has strategic collaboration and license agreements with Viatris Inc. and Bristol-Myers Squibb Company. The company was incorporated in 1995 and is headquartered in The Woodlands, Texas.

FAQ

Is LXRX financially healthy?

LEXICON PHARMACEUTICALS, INC.'s Piotroski F-score is 3/9 (8–9 is excellent, 0–3 weak).

Does LXRX pay a dividend?

No, LEXICON PHARMACEUTICALS, INC. does not currently pay a dividend.

How profitable is LXRX?

In FY2025, LEXICON PHARMACEUTICALS, INC. had a net margin of -101.1% and a return on equity of -46.8%.

What is the analyst price target for LXRX?

The average Wall-Street price target for LEXICON PHARMACEUTICALS, INC. is $3.77, about 60.4% above the recent price, from 5 analysts (consensus: buy).

Is LXRX a good stock to buy?

Stocktoria doesn't give buy or sell advice, but here is the data on LEXICON PHARMACEUTICALS, INC.: a Piotroski F-score of 3/9. Weigh these quality and valuation signals against your own goals.

Computed from company filings · US · as of 2025-12-31. Facts plus Stocktoria's own computed scores — not investment advice.