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LEXICON PHARMACEUTICALS, INC. LXRX

Nasdaq · stock · Pharmaceutical Preparations · website · IPO 2000-04-07

LEXICON PHARMACEUTICALS, INC. statistics & valuation

Market cap$1.1B
P / S22.7×
P / B10.5×
Net margin-101.1%
Return on equity-46.8%
FCF margin-136.2%
Net debt$15.1M
Enterprise value USD$1.1B
Earnings yield EBIT/EV-4.3%
Return on capital-29.8%

Market cap as of 2026-06-29. Multiples are price-derived and refreshed daily; everything else from the latest financial reports.

Profitability & efficiency

Net margin (%)
-165.80% -134.10% -190.70% 40.40% -244.10% -29449.00% -73341.00% -14710.90% -644.80% -101.10% 2016201720182019202020212022202320242025
Gross margin (%)
2016201720182019202020212022202320242025
Operating margin (%)
-160.50% -142.50% -163.40% 43.90% -199.20% -29224.80% -72489.20% -14265.00% -634.20% -98.20% 2016201720182019202020212022202320242025
Return on equity (%)
-78.50% -180.20% 111.10% -37.50% -77.30% -87.00% -190.20% -137.30% -46.80% 2016201720182019202020212022202320242025
Shares outstanding
105.2M 105.8M 116.7M 110.8M 145.7M 165.7M 221.1M 363.0M 365.8M 2016201720182019202020212022202320242025
Net debt ($)
$54.8M $189.9M $169.5M $212.5M -$126.3M -$64.1M $2.3M $77.0M $33.6M $15.1M 2016201720182019202020212022202320242025
Share buybacks ($)
2016201720182019202020212022202320242025
Return on assets (%)
-27.60% -28.20% -42.40% 31.20% -28.70% -64.10% -52.50% -77.20% -67.20% -27.20% 2016201720182019202020212022202320242025
Free cash flow margin (%)
-221.90% -202.40% -235.30% 35.30% -596.20% -29610.10% -64875.50% -13485.60% -578.50% -136.20% 2016201720182019202020212022202320242025
Debt / equity (×)
0.61× 3.69× 2.12× 0.00× 0.00× 0.41× 1.07× 0.69× 0.46× 2016201720182019202020212022202320242025
EPS ($)
-$1.17 -$1.14 $1.16 -$0.53 -$0.60 -$0.62 -$0.80 -$0.63 -$0.14 2016201720182019202020212022202320242025

Margins and returns computed from annual filings. Falling shares outstanding = buybacks; rising = dilution. Net debt = debt − cash (negative = net cash).

Key ratios (by fiscal year)

RatioFY2025FY2024FY2023FY2022FY2021FY2020FY2019FY2018FY2017FY2016
Operating margin-98.2%-634.2%-14265.0%-72489.2%-29224.8%-199.2%43.9%-163.4%-142.5%-160.5%
Net margin-101.1%-644.8%-14710.9%-73341.0%-29449.0%-244.1%40.4%-190.7%-134.1%-165.8%
FCF margin-136.2%-578.5%-13485.6%-64875.5%-29610.1%-596.2%35.3%-235.3%-202.4%-221.9%
Return on assets-27.2%-67.2%-77.2%-52.5%-64.1%-28.7%31.2%-42.4%-28.2%-27.6%
Return on equity-46.8%-137.3%-190.2%-87.0%-77.3%-37.5%111.1%456.5%-180.2%-78.5%
Debt / equity0.46×0.69×1.07×0.41×0.00×0.00×2.12×-9.46×3.69×0.61×
Current ratio4.885.445.606.084.023.375.174.723.052.17

Computed from company filings · US · as of 2025-12-31. Facts plus Stocktoria's own computed scores — not investment advice.