Stocktoria

Lyra Therapeutics, Inc. LYRA

OTC · stock · Surgical & Medical Instruments & Apparatus · website · IPO 2020-05-01

Lyra Therapeutics, Inc. (LYRA) earns a Piotroski F-score of 2/9 (weak financial health). It does not currently pay a dividend. FY2025 revenue was $398,000 at a -7266.1% net margin.

$6.53 high · $0.01 low · daily closes (~2y) · hover for date & price
13/100
Stocktoria Quality Score · grade D
2/9
Piotroski F — financial health
—
Altman Z″ — distress risk
—
Dividend yield · no dividend

Quality score trend · recomputed for each fiscal year

Piotroski F /9
3 1 4 1 3 2 202020212022202320242025
Altman Z″
10.21 -11.53 -2.76 -4.59 202020212022202320242025

Each year's score is computed from that year's filing — a rising Piotroski F or Altman Z″ means improving financial health, a fall is worth a look.

$0.20 as of 2026-09-01 · -96.9% 1y
$0.01$6.5352-wk
Market cap USD$1M
Net margin 5y avg-7340.7%
Return on equity 5y avg-267.8%
Beta0.69
Employees27
Revenue trend · last 5y · up

How it ranks in Manufacturing · percentile among 2036 companies

Piotroski Fstronger than 12%
Net marginstronger than 4%

Percentile vs other Manufacturing companies we cover — e.g. “stronger than 90%” means only 10% score higher on that measure.

Piotroski F breakdown · 2/9 tests passed

Sector peers · similar-size Manufacturing companies compare side by side →

TickerCompanyPiotroski FAltman Z″P / ERevenue growth
LYRALyra Therapeutics, Inc.2/9———
PLSEPULSE BIOSCIENCES, INC.2/9-10.11——
QTEXQTREX Quantum Ltd.2/9———
FOFAFAMILY OFFICE OF AMERICA, INC.2/9-13.31——
SKYASkyAI, Inc.3/9———
CODXCo-Diagnostics, Inc.1/9-16.26——
PAVMPAVmed Inc.3/9—90.2—

All Manufacturing companies →

About Lyra Therapeutics, Inc.

Lyra Therapeutics, Inc., a clinical-stage biotechnology company, focuses on the development and commercialization of anti-inflammatory therapies for the treatment of patients with chronic rhinosinusitis. Its technology is designed to deliver medicines directly to the affected tissue for sustained periods with a single administration. The company's product candidates include LYR-210, an anti-inflammatory implantable drug matrix which is in Phase III clinical trial for the treatment of chronic rhinosinusitis (CRS); and LYR-220 for CRS patients who have failed previous medical management and continue to require treatment to manage CRS symptoms. It has a collaboration agreement with LianBio Inflammatory Limited to develop and commercialize LYR-210 in mainland China, Hong Kong, Taiwan, Macau, South Korea, Singapore, and Thailand. The company was formerly known as 480 Biomedical, Inc. and changed its name to Lyra Therapeutics, Inc. in July 2018. Lyra Therapeutics, Inc. was incorporated in 2005 and is headquartered in Watertown, Massachusetts.

FAQ

Is LYRA financially healthy?

Lyra Therapeutics, Inc.'s Piotroski F-score is 2/9 (8–9 is excellent, 0–3 weak).

Does LYRA pay a dividend?

No, Lyra Therapeutics, Inc. does not currently pay a dividend.

How profitable is LYRA?

In FY2025, Lyra Therapeutics, Inc. had a net margin of -7266.1%.

Is LYRA a good stock to buy?

Stocktoria doesn't give buy or sell advice, but here is the data on Lyra Therapeutics, Inc.: a Piotroski F-score of 2/9. Weigh these quality and valuation signals against your own goals.

Computed from company filings · US · as of 2025-12-31. Facts plus Stocktoria's own computed scores — not investment advice.