Stocktoria

MADRIGAL PHARMACEUTICALS, INC. MDGL

Nasdaq · stock · Pharmaceutical Preparations · website · IPO 2007-02-06 · LEI

MADRIGAL PHARMACEUTICALS, INC. (MDGL) earns a Piotroski F-score of 3/9 (weak financial health), with an Altman Z″ in the distress zone. It does not currently pay a dividend. FY2025 revenue was $958.4M at a -30.1% net margin.

Chart by TradingView
30/100
Stocktoria Quality Score · grade D
3/9
Piotroski F — financial health
-1.18
Altman Z″ — distress risk · distress
Dividend yield · no dividend

Quality score trend · recomputed for each fiscal year

Piotroski F /9
2 3 3 1 1 1 2 4 5 3 2016201720182019202020212022202320242025
Altman Z″
3.69 1.14 -6.58 -8.40 -3.67 -0.66 -1.18 2016201720182019202020212022202320242025

Each year's score is computed from that year's filing — a rising Piotroski F or Altman Z″ means improving financial health, a fall is worth a look.

$536.20 as of 2026-08-01 · +22.5% 1y
$418.90$596.9852-wk
Market cap USD$11.8B
Net margin 5y avg-144.4%
Return on equity 5y avg-94.9%
Beta-1
Employees915

Analyst price target

$678.06 +26.5% vs last
consensus: strong buy · 16 analysts
target range $543.00 – $962.00 · median $651.50
3 strong buy · 13 buy · 1 hold
Recent analyst actions
DateFirmRating
2026-08-04Wolfe ResearchOutperform (up)
2026-08-03BarclaysOverweight (main)
2026-07-29Canaccord GenuityBuy (main)
2026-07-27Wells FargoOverweight (init)
2026-06-11B of A SecuritiesNeutral (main)
2026-05-13Truist SecuritiesBuy (main)

Wall Street analyst consensus — a sentiment gauge, not our scoring.

Forward estimates · earnings calendar →

Forward EPS est.$9.62
Forward P / E55.7×

Consensus analyst estimates and scheduled dates — forward-looking, may change.

Smart money · insiders, last 12 months

Insiders net sold -$4.7M on the open market · 26 trades

Open-market insider purchases minus sells (SEC Form 4) — real buying with their own money is a bullish “smart money” signal; grants and option exercises are excluded.

Revenue trend · last 9y · up

How it ranks in Manufacturing · percentile among 1957 companies

Piotroski Fstronger than 27%
Net marginstronger than 32%
Return on equitystronger than 30%
Revenue growthstronger than 99%

Percentile vs other Manufacturing companies we cover — e.g. “stronger than 90%” means only 10% score higher on that measure.

Piotroski F breakdown · 3/9 tests passed

Altman Z″ components · distress zone

ComponentValue
Working capital / assets0.743
Retained earnings / assets-1.66
EBIT / assets-0.238
Equity / liabilities0.917

Sector peers · similar-size Manufacturing companies compare side by side →

TickerCompanyPiotroski FAltman Z″P / ERevenue growth
MDGLMADRIGAL PHARMACEUTICALS, INC.3/9-1.18+432.1%
IONSIONIS PHARMACEUTICALS INC3/91.12+33.8%
ANIPANI PHARMACEUTICALS INC6/93.2624.5+43.8%
HRMYHarmony Biosciences Holdings, Inc.5/97.1712.9+21.5%
ACADACADIA PHARMACEUTICALS INC4/93.7911.1+11.9%
ARWRARROWHEAD PHARMACEUTICALS, INC.4/90.82
PBHPrestige Consumer Healthcare Inc.5/94.0412.3-4.3%

All Manufacturing companies →

About MADRIGAL PHARMACEUTICALS, INC.

Madrigal Pharmaceuticals, Inc., a biopharmaceutical company, focuses on delivering novel therapeutics for metabolic dysfunction-associated steatohepatitis (MASH) in the United States. It offers Rezdiffra, a liver-directed thyroid hormone receptor beta agonist for treating MASH. The company was founded in 2016 and is headquartered in West Conshohocken, Pennsylvania.

FAQ

Is MDGL financially healthy?

MADRIGAL PHARMACEUTICALS, INC.'s Piotroski F-score is 3/9 (8–9 is excellent, 0–3 weak), and its Altman Z″ distress score is in the distress zone.

Does MDGL pay a dividend?

No, MADRIGAL PHARMACEUTICALS, INC. does not currently pay a dividend.

How profitable is MDGL?

In FY2025, MADRIGAL PHARMACEUTICALS, INC. had a net margin of -30.1% and a return on equity of -47.8%.

What is the analyst price target for MDGL?

The average Wall-Street price target for MADRIGAL PHARMACEUTICALS, INC. is $678.06, about 26.5% above the recent price, from 16 analysts (consensus: strong buy).

Is MDGL a good stock to buy?

Stocktoria doesn't give buy or sell advice, but here is the data on MADRIGAL PHARMACEUTICALS, INC.: a Piotroski F-score of 3/9, an Altman Z″ in the distress zone. Weigh these quality and valuation signals against your own goals.

Computed from company filings · US · as of 2025-12-31. Facts plus Stocktoria's own computed scores — not investment advice.