Stocktoria

Orchestra BioMed Holdings, Inc. OBIO

Nasdaq · stock · Surgical & Medical Instruments & Apparatus · website · IPO 2020-08-04

Orchestra BioMed Holdings, Inc. (OBIO) earns a Piotroski F-score of 5/9 (mixed financial health), with an Altman Z″ in the distress zone. It does not currently pay a dividend. FY2025 revenue was $33.5M at a -157.4% net margin.

Chart by TradingView
27/100
Stocktoria Quality Score · grade D
5/9
Piotroski F — financial health
-7.02
Altman Z″ — distress risk · distress
Dividend yield · no dividend

Quality score trend · recomputed for each fiscal year

Piotroski F /9
2 2 2 5 2022202320242025
Altman Z″
-3.29 -4.16 -13.57 -7.02 2022202320242025

Each year's score is computed from that year's filing — a rising Piotroski F or Altman Z″ means improving financial health, a fall is worth a look.

$4.42 as of 2026-08-01 · +61.9% 1y
$2.48$5.3252-wk
Market cap USD$254M
Net margin 5y avg-1300.4%
Return on equity 5y avg-105%
Beta0.5
Employees86

Analyst price target

$12.17 +175.3% vs last
· 6 analysts
target range $9.00 – $20.00

Wall Street analyst consensus — a sentiment gauge, not our scoring.

Revenue trend · last 4y · up

How it ranks in Manufacturing · percentile among 1957 companies

Piotroski Fstronger than 63%
Net marginstronger than 20%
Return on equitystronger than 19%

Percentile vs other Manufacturing companies we cover — e.g. “stronger than 90%” means only 10% score higher on that measure.

Piotroski F breakdown · 5/9 tests passed

Altman Z″ components · distress zone

ComponentValue
Working capital / assets0.794
Retained earnings / assets-3.157
EBIT / assets-0.451
Equity / liabilities1.041

Sector peers · similar-size Manufacturing companies compare side by side →

TickerCompanyPiotroski FAltman Z″P / ERevenue growth
OBIOOrchestra BioMed Holdings, Inc.5/9-7.02
SSKNSTRATA Skin Sciences, Inc.4/9-8.5%
CTSOCytosorbents Corp3/9+4.1%
UTMDUTAH MEDICAL PRODUCTS INC3/9-5.8%
IDXGINTERPACE BIOSCIENCES, INC.4/9-16.521.9-17.5%
SRTSSensus Healthcare, Inc.4/914.36-34.3%
KRMDKORU Medical Systems, Inc.4/9-0.06+22.2%

All Manufacturing companies →

About Orchestra BioMed Holdings, Inc.

Orchestra BioMed Holdings, Inc. operates as a biomedical company in the United States. The company's flagship product candidates include Atrioventricular Interval Modulation, a bioelectronic therapy candidate designed to immediately, substantially, and persistently lower blood pressure; and Virtue Sirolimus AngioInfusion Balloon for the treatment of atherosclerotic artery disease. It also develops Cardiac Neuromodulation Therapy for heart failure, or potential treatment of clinical indications, such as urology or osteoarthritis; and CNT-HF, a bioelectronic product candidate that aims to reduce chronic sympathetic nervous system activity in heart failure. In addition, the company offers FreeHold devices and additional minimally invasive surgery enabling devices; and Pure-Vu system, a medical device to facilitate the cleansing of a poorly prepared gastrointestinal tract during colonoscopy and upper gastrointestinal endoscopy procedures. It has a collaboration agreement with Medtronic, Inc. for the development of AVIM therapy for the treatment of HTN in pacemaker-indicated patients; and a strategic collaboration with Terumo Corporation and Terumo Medical Corporation for the development and commercialization of Virtue SAB for the treatment of coronary and peripheral vascular disease. Orchestra BioMed Holdings, Inc. was founded in 2018 and is headquartered in New Hope, Pennsylvania.

FAQ

Is OBIO financially healthy?

Orchestra BioMed Holdings, Inc.'s Piotroski F-score is 5/9 (8–9 is excellent, 0–3 weak), and its Altman Z″ distress score is in the distress zone.

Does OBIO pay a dividend?

No, Orchestra BioMed Holdings, Inc. does not currently pay a dividend.

How profitable is OBIO?

In FY2025, Orchestra BioMed Holdings, Inc. had a net margin of -157.4% and a return on equity of -98.4%.

What is the analyst price target for OBIO?

The average Wall-Street price target for Orchestra BioMed Holdings, Inc. is $12.17, about 175.3% above the recent price, from 6 analysts.

Is OBIO a good stock to buy?

Stocktoria doesn't give buy or sell advice, but here is the data on Orchestra BioMed Holdings, Inc.: a Piotroski F-score of 5/9, an Altman Z″ in the distress zone. Weigh these quality and valuation signals against your own goals.

Computed from company filings · US · as of 2025-12-31. Facts plus Stocktoria's own computed scores — not investment advice.