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OPKO HEALTH, INC. OPK

Nasdaq · stock · Pharmaceutical Preparations · website · IPO 1995-11-02 · LEI

OPKO HEALTH, INC. statistics & valuation

Market cap$1.2B
P / S1.9×
P / B0.9×
Net margin-37.2%
Return on equity-17.8%
Net cash$20.4M
Enterprise value USD$1.1B
Earnings yield EBIT/EV-10.3%
Return on capital-6.6%

Market cap as of 2026-06-29. Multiples are price-derived and refreshed daily; everything else from the latest financial reports.

Profitability & efficiency

Net margin (%)
-4.00% -28.60% -15.50% -34.90% 2.10% -1.70% -32.70% -21.90% -7.50% -37.20% 2016201720182019202020212022202320242025
Gross margin (%)
28.70% 36.80% 30.60% 33.90% 2016201720182019202020212022202320242025
Operating margin (%)
-7.90% -25.90% -17.30% -30.40% 4.00% 1.10% -22.50% -18.20% -21.30% -19.30% 2016201720182019202020212022202320242025
Return on equity (%)
-2.40% -16.60% -8.50% -19.50% 1.80% -1.80% -21.00% -13.60% -3.90% -17.80% 2016201720182019202020212022202320242025
Shares outstanding
555.6M 559.2M 563.1M 595.5M 640.7M 648.1M 719.1M 751.8M 694.0M 751.1M 2016201720182019202020212022202320242025
Net debt ($)
-$168.0M -$89.9M -$91.8M $184.8M $179.0M $70.6M $103.1M -$88.2M $10.6M -$20.4M 2016201720182019202020212022202320242025
Share buybacks ($)
2016201720182019202020212022202320242025
Return on assets (%)
-1.70% -11.80% -6.20% -13.60% 1.20% -1.30% -15.20% -9.40% -2.40% -11.70% 2016201720182019202020212022202320242025
Free cash flow margin (%)
2016201720182019202020212022202320242025
Debt / equity (×)
0.00× 0.00× 0.00× 0.17× 0.15× 0.12× 0.16× 0.01× 0.32× 0.27× 2016201720182019202020212022202320242025
EPS ($)
-$0.10 -$0.55 -$0.27 -$0.53 $0.05 -$0.05 -$0.46 -$0.25 -$0.08 -$0.30 2016201720182019202020212022202320242025

Margins and returns computed from annual filings. Falling shares outstanding = buybacks; rising = dilution. Net debt = debt − cash (negative = net cash).

Key ratios (by fiscal year)

RatioFY2025FY2024FY2023FY2022FY2021FY2020FY2019FY2018FY2017FY2016
Gross margin33.9%30.6%36.8%28.7%——————
Operating margin-19.3%-21.3%-18.2%-22.5%1.1%4.0%-30.4%-17.3%-25.9%-7.9%
Net margin-37.2%-7.5%-21.9%-32.7%-1.7%2.1%-34.9%-15.5%-28.6%-4.0%
Return on assets-11.7%-2.4%-9.4%-15.2%-1.3%1.2%-13.6%-6.2%-11.8%-1.7%
Return on equity-17.8%-3.9%-13.6%-21.0%-1.8%1.8%-19.5%-8.5%-16.6%-2.4%
Debt / equity0.27×0.32×0.01×0.16×0.12×0.15×0.17×0.00×0.00×0.00×
Current ratio3.973.431.551.852.491.391.301.101.121.84

Computed from company filings · US · as of 2025-12-31. Facts plus Stocktoria's own computed scores — not investment advice.