Stocktoria

PALISADE BIO, INC. PALI

Nasdaq · stock · Biological Products, (No Diagnostic Substances) · website · IPO 2006-12-20

PALISADE BIO, INC. (PALI) earns a Piotroski F-score of 3/9 (weak financial health). It does not currently pay a dividend.

Chart by TradingView
33/100
Stocktoria Quality Score · grade D
3/9
Piotroski F — financial health
Altman Z″ — distress risk
Dividend yield · no dividend

Quality score trend · recomputed for each fiscal year

Piotroski F /9
4 3 3 1 3 5 3 5 1 3 2016201720182019202020212022202320242025
Altman Z″
8.40 2016201720182019202020212022202320242025

Each year's score is computed from that year's filing — a rising Piotroski F or Altman Z″ means improving financial health, a fall is worth a look.

$1.96 as of 2026-08-01 · +188.2% 1y
$0.68$2.3552-wk
Market cap USD$328M
Net margin 5y avg-4100%
Return on equity 5y avg-158%
Beta1.53
Employees14

Analyst price target

$10.50 +435.7% vs last
consensus: strong buy · 8 analysts
target range $5.00 – $25.00

Wall Street analyst consensus — a sentiment gauge, not our scoring.

Smart money · insiders, last 12 months

Insiders net sold -$1,943 on the open market · 3 trades

Open-market insider purchases minus sells (SEC Form 4) — real buying with their own money is a bullish “smart money” signal; grants and option exercises are excluded.

Revenue trend · last 9y · down

How it ranks in Manufacturing · percentile among 1957 companies

Piotroski Fstronger than 27%
Return on equitystronger than 47%

Percentile vs other Manufacturing companies we cover — e.g. “stronger than 90%” means only 10% score higher on that measure.

Piotroski F breakdown · 3/9 tests passed

Sector peers · similar-size Manufacturing companies compare side by side →

TickerCompanyPiotroski FAltman Z″P / ERevenue growth
PALIPALISADE BIO, INC.3/9
AMGNAMGEN INC6/90.1425.1+10%
GILDGILEAD SCIENCES, INC.7/93.2818.7+2.4%
BIIBBIOGEN INC.4/924.7+2.2%
NBIXNEUROCRINE BIOSCIENCES INC5/96.2135.4+21.4%
EXELEXELIXIS, INC.6/97.6917.6+7%
QGENQIAGEN N.V.7/95.0619.1+5.7%

All Manufacturing companies →

About PALISADE BIO, INC.

Palisade Bio, Inc., a clinical-stage biopharmaceutical company, engages in developing oral phosphodiesterase-4 inhibitor prodrugs designed for targeted delivery to the terminal ileum and colon in the United States. Its lead clinical product candidate includes PALI-2108, which is in phase 1b clinical trial to treat patients with inflammatory bowel disease, including ulcerative colitis and Fibrostenotic Crohn's disease. The company has a research collaboration and license agreement with Giiant Pharma, Inc. for the development, manufacture, and commercialization of its compounds; license agreement with the Regents of the University of California for sole purpose of maintaining the Newsoara Co-Development; and a co-development and distribution agreement with Newsoara Biopharma Co., Ltd. The company was founded in 2001 and is headquartered in Denver, Colorado.

FAQ

Is PALI financially healthy?

PALISADE BIO, INC.'s Piotroski F-score is 3/9 (8–9 is excellent, 0–3 weak).

Does PALI pay a dividend?

No, PALISADE BIO, INC. does not currently pay a dividend.

How profitable is PALI?

In FY2025, PALISADE BIO, INC. had a return on equity of -13.0%.

What is the analyst price target for PALI?

The average Wall-Street price target for PALISADE BIO, INC. is $10.50, about 435.7% above the recent price, from 8 analysts (consensus: strong buy).

Is PALI a good stock to buy?

Stocktoria doesn't give buy or sell advice, but here is the data on PALISADE BIO, INC.: a Piotroski F-score of 3/9. Weigh these quality and valuation signals against your own goals.

Computed from company filings · US · as of 2025-12-31. Facts plus Stocktoria's own computed scores — not investment advice.