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PUMA BIOTECHNOLOGY, INC. PBYI

Nasdaq · stock · Pharmaceutical Preparations · website · IPO 2012-03-21

PUMA BIOTECHNOLOGY, INC. statistics & valuation

Market cap$412.8M
P / E13.3×
P / S1.8×
P / B3.2×
P / FCF9.9×
Net margin13.6%
Return on equity23.9%
FCF margin18.3%
Net cash$7.0M
Net debt / EBITDA-0.1×
Enterprise value USD$405.8M
EV / EBITDA8.4×
Earnings yield EBIT/EV9.2%
Return on capital27.6%
Graham number -33.2%$5.94

Market cap as of 2026-06-29. Multiples are price-derived and refreshed daily; everything else from the latest financial reports. The Graham number is Benjamin Graham's rough maximum fair value ($5.94); a green figure means the price is below it.

Profitability & efficiency

Net margin (%)
-1054.60% -45.30% -27.80% -26.70% -11.50% 0.00% 9.20% 13.10% 13.60% 2016201720182019202020212022202320242025
Gross margin (%)
2016201720182019202020212022202320242025
Operating margin (%)
-1056.10% -37.70% -14.30% -13.50% 0.50% 10.40% 13.90% 13.40% 16.30% 2016201720182019202020212022202320242025
Return on equity (%)
-131.50% -547.70% -331.10% -432.90% 0.00% 40.40% 32.90% 23.90% 2016201720182019202020212022202320242025
Shares outstanding
36.8M 37.6M 38.3M 39.2M 40.1M 41.2M 46.3M 47.6M 49.1M 50.7M 2016201720182019202020212022202320242025
Net debt ($)
-$33.2M $43.5M $34.9M -$1.3M $38.9M $25.8M $17.4M -$1.2M -$7.0M 2016201720182019202020212022202320242025
Share buybacks ($)
2016201720182019202020212022202320242025
Return on assets (%)
-109.20% -176.40% -43.80% -32.20% -24.60% -12.90% 0.00% 9.40% 14.20% 14.40% 2016201720182019202020212022202320242025
Free cash flow margin (%)
-624.50% -9.80% 8.10% 0.30% 8.20% -6.90% 11.40% 16.90% 18.30% 2016201720182019202020212022202320242025
Debt / equity (×)
0.91× 4.43× 5.44× 4.72× 1.91× 0.74× 0.17× 2016201720182019202020212022202320242025
EPS ($)
-$1.52 -$0.72 $0.00 $0.45 $0.62 $0.61 2016201720182019202020212022202320242025

Margins and returns computed from annual filings. Falling shares outstanding = buybacks; rising = dilution. Net debt = debt − cash (negative = net cash).

Key ratios (by fiscal year)

RatioFY2025FY2024FY2023FY2022FY2021FY2020FY2019FY2018FY2017FY2016
Operating margin16.3%13.4%13.9%10.4%0.5%-13.5%-14.3%-37.7%-1056.1%—
Net margin13.6%13.1%9.2%0.0%-11.5%-26.7%-27.8%-45.3%-1054.6%—
FCF margin18.3%16.9%11.4%-6.9%8.2%0.3%8.1%-9.8%-624.5%—
Return on assets14.4%14.2%9.4%0.0%-12.9%-24.6%-32.2%-43.8%-176.4%-109.2%
Return on equity23.9%32.9%40.4%0.0%1190.8%1008.1%-432.9%-331.1%-547.7%-131.5%
Debt / equity0.17×0.74×1.91×4.72×-41.70×-14.12×5.44×4.43×0.91×—
Current ratio2.001.541.571.731.281.281.833.021.826.31

Computed from company filings · US · as of 2025-12-31. Facts plus Stocktoria's own computed scores — not investment advice.