Stocktoria

Protalix BioTherapeutics, Inc. PLX

NYSE · stock · Biological Products, (No Diagnostic Substances) · website · IPO 2010-09-06 · LEI

Protalix BioTherapeutics, Inc. (PLX) earns a Piotroski F-score of 2/9 (weak financial health), with an Altman Z″ in the distress zone. It does not currently pay a dividend. FY2025 revenue was $52.7M at a -12.5% net margin.

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19/100
Stocktoria Quality Score · grade D
2/9
Piotroski F — financial health
-11.01
Altman Z″ — distress risk · distress
Dividend yield · no dividend
-0.17
Beneish M-score — earnings quality · elevated

Quality score trend · recomputed for each fiscal year

Piotroski F /9
1 4 4 3 1 2 2 3 5 2 2016201720182019202020212022202320242025
Altman Z″
-10.80 -13.26 -16.85 -19.67 -16.00 -11.31 -11.86 -11.01 2016201720182019202020212022202320242025

Each year's score is computed from that year's filing — a rising Piotroski F or Altman Z″ means improving financial health, a fall is worth a look.

$2.62 as of 2026-08-01 · +69% 1y
$1.55$2.8852-wk

Beneish M-score: -0.17 — elevated (above the −1.78 line — aggressive-accounting signals worth a closer look) . A statistical screen for earnings manipulation, not proof — and it doesn't apply to most banks/insurers.

Market cap USD$189M
Net margin 5y avg-19.5%
Beta0.01
Employees226

Analyst price target

$11.00 +319.8% vs last
· 2 analysts
target range $10.00 – $12.00

Wall Street analyst consensus — a sentiment gauge, not our scoring.

Revenue trend · last 10y · up

How it ranks in Manufacturing · percentile among 1957 companies

Piotroski Fstronger than 12%
Net marginstronger than 39%
Return on equitystronger than 46%
Revenue growthstronger than 31%

Percentile vs other Manufacturing companies we cover — e.g. “stronger than 90%” means only 10% score higher on that measure.

Piotroski F breakdown · 2/9 tests passed

Altman Z″ components · distress zone

ComponentValue
Working capital / assets0.488
Retained earnings / assets-4.675
EBIT / assets-0.067
Equity / liabilities1.414

Sector peers · similar-size Manufacturing companies compare side by side →

TickerCompanyPiotroski FAltman Z″P / ERevenue growth
PLXProtalix BioTherapeutics, Inc.2/9-11.01-1.2%
IVVDInvivyd, Inc.2/9-0.36+110.5%
CSBRCHAMPIONS ONCOLOGY, INC.5/9-7.27+4.4%
FENCFENNEC PHARMACEUTICALS INC.-4.88-6.1%
CHRSCoherus Oncology, Inc.4/91.4+59.8%
EDITEditas Medicine, Inc.1/9+25.4%
VYGRVoyager Therapeutics, Inc.1/9-1.03-49.5%

All Manufacturing companies →

About Protalix BioTherapeutics, Inc.

Protalix BioTherapeutics, Inc., a biopharmaceutical company, engages in the development, production, and commercialization of recombinant therapeutic proteins based on the ProCellEx plant cell-based protein expression system. The company provides Elelyso for the treatment of Gaucher disease; and Elfabrio for the treatment of adult patients with a confirmed diagnosis of Fabry disease. It is also developing PRX-115, a plant cell expressed recombinant PEGylated Uricase, which is in Phase 2 trial for the treatment of gout; and PRX-119, a plant cell expressed PEGylated recombinant human DNase I product candidate for the treatment of neutrophil extracellular traps diseases. The company has agreements and partnerships with Pfizer; Fundação Oswaldo Cruz; and Chiesi Farmaceutici S.p.A. Protalix BioTherapeutics, Inc. has strategic partnership with Secarna Pharmaceuticals GmbH & Co KG. The company is headquartered in Hackensack. New Jersey.

FAQ

Is PLX financially healthy?

Protalix BioTherapeutics, Inc.'s Piotroski F-score is 2/9 (8–9 is excellent, 0–3 weak), and its Altman Z″ distress score is in the distress zone.

Does PLX pay a dividend?

No, Protalix BioTherapeutics, Inc. does not currently pay a dividend.

How profitable is PLX?

In FY2025, Protalix BioTherapeutics, Inc. had a net margin of -12.5% and a return on equity of -13.7%.

What is the analyst price target for PLX?

The average Wall-Street price target for Protalix BioTherapeutics, Inc. is $11.00, about 319.8% above the recent price, from 2 analysts.

Is PLX a good stock to buy?

Stocktoria doesn't give buy or sell advice, but here is the data on Protalix BioTherapeutics, Inc.: a Piotroski F-score of 2/9, an Altman Z″ in the distress zone. Weigh these quality and valuation signals against your own goals.

Computed from company filings · US · as of 2025-12-31. Facts plus Stocktoria's own computed scores — not investment advice.