Stocktoria

Praxis Precision Medicines, Inc. PRAX

Nasdaq · stock · Pharmaceutical Preparations · website · IPO 2020-10-16

Praxis Precision Medicines, Inc. (PRAX) earns a Piotroski F-score of 2/9 (weak financial health), with an Altman Z″ in the safe zone. It does not currently pay a dividend.

Chart by TradingView
55/100
Stocktoria Quality Score · grade C
2/9
Piotroski F — financial health
12.98
Altman Z″ — distress risk · safe
Dividend yield · no dividend

Quality score trend · recomputed for each fiscal year

Piotroski F /9
3 1 2 4 3 2 202020212022202320242025
Altman Z″
4.49 8.97 12.98 202020212022202320242025

Each year's score is computed from that year's filing — a rising Piotroski F or Altman Z″ means improving financial health, a fall is worth a look.

$386.33 as of 2026-08-01 · +748.3% 1y
$45.54$386.3352-wk
Market cap USD$9.1B
Net margin 5y avg-3587.7%
Return on equity 5y avg-120%
Beta2.78
Employees168

Analyst price target

$623.68 +61.4% vs last
consensus: strong buy · 19 analysts
target range $188.00 – $1,201.00 · median $550.00
3 strong buy · 14 buy · 1 hold · 1 sell
Recent analyst actions
DateFirmRating
2026-08-07RBC CapitalOutperform (main)
2026-08-07Wells FargoEqual-Weight (main)
2026-08-06NeedhamBuy (main)
2026-07-29BTIGBuy (reit)
2026-07-13Goldman SachsBuy (init)
2026-06-29NeedhamBuy (main)

Wall Street analyst consensus — a sentiment gauge, not our scoring.

Forward estimates · earnings calendar →

Forward EPS est.$-9.41

Consensus analyst estimates and scheduled dates — forward-looking, may change.

Revenue trend · last 4y · up

How it ranks in Manufacturing · percentile among 1957 companies

Piotroski Fstronger than 12%
Return on equitystronger than 35%

Percentile vs other Manufacturing companies we cover — e.g. “stronger than 90%” means only 10% score higher on that measure.

Piotroski F breakdown · 2/9 tests passed

Altman Z″ components · safe zone

ComponentValue
Working capital / assets0.588
Retained earnings / assets-1.215
EBIT / assets-0.348
Equity / liabilities14.692

Sector peers · similar-size Manufacturing companies compare side by side →

TickerCompanyPiotroski FAltman Z″P / ERevenue growth
PRAXPraxis Precision Medicines, Inc.2/912.98
JNJJOHNSON & JOHNSON4/922.9+6%
LLYELI LILLY & Co7/955.1+44.7%
MRKMerck & Co., Inc.4/917.4+1.3%
PFEPFIZER INC4/917.8-1.6%
ABBVAbbVie Inc.7/9-0.34105.9+8.6%
BMYBRISTOL MYERS SQUIBB CO7/916.7-0.2%

All Manufacturing companies →

About Praxis Precision Medicines, Inc.

Praxis Precision Medicines, Inc., a clinical-stage biopharmaceutical company, engages in the development of therapies for central nervous system (CNS) disorders characterized by neuronal excitation-inhibition imbalance in the United States. The company's platforms include Cerebrum, a small molecule platform for CNS small molecule therapies to develop orally available precision therapies; and Solidus to discover and develop antisense oligonucleotide. It also develops ulixacaltamide, a small molecule inhibitor of T-type calcium channels that in NDA for the treatment of essential tremor; relutrigine, a small molecule, which is in NDA for the treatment of SCN2A- and SCN8A-developmental and epileptic encephalopathies (DEE), as well as in Phase 3 trial for broad DEEs; vormatrigine, a small molecule targeting the hyperexcitable state of sodium-channels in the brain that is in Phase 3 trial for the treatment of adjunctive focal epilepsy, as well as in Phase 2 trial for monotherapy focal epilepsy; and Elsunersen, a clinical-stage ASO designed to selectively decrease SCN2A gene expression, which is in Phase 3 trial for the treatment of SCN2A-DEE. In addition, the company is developing product candidates in pre-clinical trial comprising PRAX-020 to treat KCNT1; PRAX-080 that targets PCDH19 mosaic expression disorders; PRAX-090 for targeting SYNGAP1 loss-of-function; and PRAX-100 that targets SCN2A LoF mutations. It has a cooperation and license agreement with RogCon Inc.; research collaboration, option, and license agreement with Ionis Pharmaceuticals, Inc.; and research collaboration and license agreement to develop an iontophoretic transdermal patch for the delivery of ulixacaltamide. The company was formerly known as EpiPM Therapeutics, Inc. and changed its name to Praxis Precision Medicines, Inc. in October 2016. Praxis Precision Medicines, Inc. was incorporated in 2015 and is headquartered in Boston, Massachusetts.

FAQ

Is PRAX financially healthy?

Praxis Precision Medicines, Inc.'s Piotroski F-score is 2/9 (8–9 is excellent, 0–3 weak), and its Altman Z″ distress score is in the safe zone.

Does PRAX pay a dividend?

No, Praxis Precision Medicines, Inc. does not currently pay a dividend.

How profitable is PRAX?

In FY2025, Praxis Precision Medicines, Inc. had a return on equity of -34.5%.

What is the analyst price target for PRAX?

The average Wall-Street price target for Praxis Precision Medicines, Inc. is $623.68, about 61.4% above the recent price, from 19 analysts (consensus: strong buy).

Is PRAX a good stock to buy?

Stocktoria doesn't give buy or sell advice, but here is the data on Praxis Precision Medicines, Inc.: a Piotroski F-score of 2/9, an Altman Z″ in the safe zone. Weigh these quality and valuation signals against your own goals.

Computed from company filings · US · as of 2025-12-31. Facts plus Stocktoria's own computed scores — not investment advice.