Stocktoria

Prelude Therapeutics Inc PRLD

Nasdaq · stock · Pharmaceutical Preparations · website · IPO 2020-09-25

Prelude Therapeutics Inc (PRLD) earns a Piotroski F-score of 3/9 (weak financial health), with an Altman Z″ in the distress zone. It does not currently pay a dividend. FY2025 revenue was $12.1M at a -819.6% net margin.

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18/100
Stocktoria Quality Score · grade D
3/9
Piotroski F — financial health
-17.29
Altman Z″ — distress risk · distress
Dividend yield · no dividend

Quality score trend · recomputed for each fiscal year

Piotroski F /9
3 1 1 3 1 3 202020212022202320242025
Altman Z″
16.72 4.91 2.63 -8.93 -17.29 202020212022202320242025

Each year's score is computed from that year's filing — a rising Piotroski F or Altman Z″ means improving financial health, a fall is worth a look.

$5.73 as of 2026-08-01 · +373.6% 1y
$1.21$5.7352-wk
Market cap USD$349M
Net margin 5y avg-1318.2%
Return on equity 5y avg-78.3%
Beta1.01
Employees79

Analyst price target

$8.00 +39.6% vs last
· 3 analysts
target range $6.00 – $10.00

Wall Street analyst consensus — a sentiment gauge, not our scoring.

Revenue trend · last 2y · up

How it ranks in Manufacturing · percentile among 1957 companies

Piotroski Fstronger than 27%
Net marginstronger than 11%
Return on equitystronger than 13%

Percentile vs other Manufacturing companies we cover — e.g. “stronger than 90%” means only 10% score higher on that measure.

Piotroski F breakdown · 3/9 tests passed

Altman Z″ components · distress zone

ComponentValue
Working capital / assets0.373
Retained earnings / assets-4.834
EBIT / assets-0.74
Equity / liabilities0.944

Sector peers · similar-size Manufacturing companies compare side by side →

TickerCompanyPiotroski FAltman Z″P / ERevenue growth
PRLDPrelude Therapeutics Inc3/9-17.29
JAGXJaguar Health, Inc.2/9-1.5%
EVMNEvommune, Inc.2/99.47
TNXPTonix Pharmaceuticals Holding Corp.3/9-0.37+29.8%
CBIOCRESCENT BIOPHARMA, INC.4/94.59
PYXSPyxis Oncology, Inc.2/9-16.86-14.2%
ABUSArbutus Biopharma Corp3/9

All Manufacturing companies →

About Prelude Therapeutics Inc

Prelude Therapeutics Incorporated, a clinical-stage precision oncology company, focuses on the discovery and development of novel precision cancer medicines to underserved patients. It is developing JAK2V617F, a driver mutation product for the treatment of myeloproliferative neoplasms, myelofibrosis (MF), polycythemia vera, and essential thrombocythemia (ET); KAT6A for the treatment of advanced breast cancer and other solid tumors; and mutated calreticulin degrader antibody conjugates to treat MF and ET. The company has collaboration with AbCellera Biologics to discover, develop, and commercialize novel degrader antibody conjugates. Prelude Therapeutics Incorporated was incorporated in 2016 and is based in Wilmington, Delaware.

FAQ

Is PRLD financially healthy?

Prelude Therapeutics Inc's Piotroski F-score is 3/9 (8–9 is excellent, 0–3 weak), and its Altman Z″ distress score is in the distress zone.

Does PRLD pay a dividend?

No, Prelude Therapeutics Inc does not currently pay a dividend.

How profitable is PRLD?

In FY2025, Prelude Therapeutics Inc had a net margin of -819.6% and a return on equity of -145.0%.

What is the analyst price target for PRLD?

The average Wall-Street price target for Prelude Therapeutics Inc is $8.00, about 39.6% above the recent price, from 3 analysts.

Is PRLD a good stock to buy?

Stocktoria doesn't give buy or sell advice, but here is the data on Prelude Therapeutics Inc: a Piotroski F-score of 3/9, an Altman Z″ in the distress zone. Weigh these quality and valuation signals against your own goals.

Computed from company filings · US · as of 2025-12-31. Facts plus Stocktoria's own computed scores — not investment advice.