Stocktoria

PROTHENA CORP PUBLIC LTD CO PRTA

Nasdaq · stock · Pharmaceutical Preparations · website · IPO 2012-12-21

PROTHENA CORP PUBLIC LTD CO (PRTA) earns a Piotroski F-score of 1/9 (weak financial health), with an Altman Z″ in the distress zone. It does not currently pay a dividend. FY2025 revenue was $9.7M at a -2520.6% net margin.

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8/100
Stocktoria Quality Score · grade D
1/9
Piotroski F — financial health
-5.98
Altman Z″ — distress risk · distress
Dividend yield · no dividend

Quality score trend · recomputed for each fiscal year

Piotroski F /9
1 4 2 3 2 6 1 2 1 1 2016201720182019202020212022202320242025
Altman Z″
4.67 4.93 1.36 1.00 -3.26 6.31 5.84 3.42 5.27 -5.98 2016201720182019202020212022202320242025

Each year's score is computed from that year's filing — a rising Piotroski F or Altman Z″ means improving financial health, a fall is worth a look.

$9.26 as of 2026-08-01 · +12.9% 1y
$8.12$11.0652-wk
Market cap USD$525M
Net margin 5y avg-591.1%
Return on equity 5y avg-28.5%
Beta-0.32
Employees67

Analyst price target

$21.40 +131.1% vs last
· 5 analysts
target range $8.00 – $36.00

Wall Street analyst consensus — a sentiment gauge, not our scoring.

Smart money · insiders, last 12 months

Insiders net bought +$3.1M on the open market · 5 trades

Open-market insider purchases minus sells (SEC Form 4) — real buying with their own money is a bullish “smart money” signal; grants and option exercises are excluded.

Revenue trend · last 10y · up

How it ranks in Manufacturing · percentile among 1957 companies

Piotroski Fstronger than 1%
Net marginstronger than 7%
Return on equitystronger than 20%
Revenue growthstronger than 1%

Percentile vs other Manufacturing companies we cover — e.g. “stronger than 90%” means only 10% score higher on that measure.

Piotroski F breakdown · 1/9 tests passed

Altman Z″ components · distress zone

ComponentValue
Working capital / assets0.839
Retained earnings / assets-4.12
EBIT / assets-0.657
Equity / liabilities6.054

Sector peers · similar-size Manufacturing companies compare side by side →

TickerCompanyPiotroski FAltman Z″P / ERevenue growth
PRTAPROTHENA CORP PUBLIC LTD CO1/9-5.98-92.8%
PGENPRECIGEN, INC.2/9
JANXJanux Therapeutics, Inc.2/9-5.6%
CBIOCRESCENT BIOPHARMA, INC.4/94.59
ROIVRoivant Sciences Ltd.1/918.07-71.6%
COYACoya Therapeutics, Inc.2/95.24
JAGXJaguar Health, Inc.2/9-1.5%

All Manufacturing companies →

About PROTHENA CORP PUBLIC LTD CO

Prothena Corporation plc, a late-stage clinical biotechnology company, focuses on discovery and development of novel therapies to treat diseases caused by protein dysregulation. Its product pipeline includes Prasinezumab, an investigational humanized monoclonal antibody which is in Phase 3 clinical trial for the treatment of parkinson's disease and other synucleinopathies. The company also develops Coramitug, an investigational antibody, which is in Phase 3 clinical trial for the treatment of transthyretin amyloidosis; BMS-986446, an anti-tau antibody which is in Phase 2 clinical trial to treat Alzheimer's disease; PRX019, an investigational antibody which is in Phase 1 clinical trial for the treatment of neurodegenerative diseases; and PRX123, a Dual Aß-Tau Vaccine, which is in preclinical trial for treating Alzheimer's disease. In addition, it develops discovery- and late-preclinical-stage programs include TDP-43 CYTOPE for the treatment of amyotrophic lateral sclerosis; PRX012, a next-generation anti-Aß antibody which is in phase 1 clinical trial to treat Alzheimer's disease; and PRX012-TfR, a preclinical program for the treatment of Alzheimer's disease. It has a license, development, and commercialization agreement with F. Hoffmann-La Roche Ltd. and Hoffmann-La Roche Inc. to develop and commercialize antibodies that target a-synuclein, including prasinezumab; and master collaboration agreement with Bristol Myers Squibb to develop and commercialize antibodies targeting tau, TDP-43. Prothena Corporation plc was incorporated in 2012 and is based in Dublin, Ireland.

FAQ

Is PRTA financially healthy?

PROTHENA CORP PUBLIC LTD CO's Piotroski F-score is 1/9 (8–9 is excellent, 0–3 weak), and its Altman Z″ distress score is in the distress zone.

Does PRTA pay a dividend?

No, PROTHENA CORP PUBLIC LTD CO does not currently pay a dividend.

How profitable is PRTA?

In FY2025, PROTHENA CORP PUBLIC LTD CO had a net margin of -2520.6% and a return on equity of -87.0%.

What is the analyst price target for PRTA?

The average Wall-Street price target for PROTHENA CORP PUBLIC LTD CO is $21.40, about 131.1% above the recent price, from 5 analysts.

Is PRTA a good stock to buy?

Stocktoria doesn't give buy or sell advice, but here is the data on PROTHENA CORP PUBLIC LTD CO: a Piotroski F-score of 1/9, an Altman Z″ in the distress zone. Weigh these quality and valuation signals against your own goals.

Computed from company filings · US · as of 2025-12-31. Facts plus Stocktoria's own computed scores — not investment advice.