Stocktoria

RHYTHM PHARMACEUTICALS, INC. RYTM

Nasdaq · stock · Pharmaceutical Preparations · website · IPO 2017-10-05 · LEI

RHYTHM PHARMACEUTICALS, INC. statistics & valuation

Market cap$7.5B
P / S39.7×
P / B54.2×
Net margin-103.6%
Return on equity-141.3%
FCF margin-61.5%
Net debt$46.6M
Enterprise value USD$7.6B
Earnings yield EBIT/EV-2.5%
Return on capital-51.3%

Market cap as of 2026-06-29. Multiples are price-derived and refreshed daily; everything else from the latest financial reports.

Profitability & efficiency

Net margin (%)
-2207.10% -766.20% -238.50% -200.30% -103.60% 2016201720182019202020212022202320242025
Gross margin (%)
2016201720182019202020212022202320242025
Operating margin (%)
-5391.90% -757.90% -238.10% -204.00% -101.20% 2016201720182019202020212022202320242025
Return on equity (%)
-23.30% -30.10% -50.10% -80.50% -24.50% -68.50% -108.80% -1199.30% -141.30% 2016201720182019202020212022202320242025
Shares outstanding
10.2M 27.3M 34.4M 44.0M 44.2M 50.3M 56.6M 59.4M 62.4M 67.2M 2016201720182019202020212022202320242025
Net debt ($)
$46.1M $19.1M $46.6M 2016201720182019202020212022202320242025
Share buybacks ($)
2016201720182019202020212022202320242025
Return on assets (%)
-22.20% -28.50% -45.60% -71.60% -21.10% -47.40% -55.50% -66.40% -40.90% 2016201720182019202020212022202320242025
Free cash flow margin (%)
-4642.90% -734.90% -175.90% -87.50% -61.50% 2016201720182019202020212022202320242025
Debt / equity (×)
0.63× 4.98× 0.73× 2016201720182019202020212022202320242025
EPS ($)
-$3.86 -$3.04 -$1.40 -$3.47 -$3.20 -$4.34 -$3.11 2016201720182019202020212022202320242025

Margins and returns computed from annual filings. Falling shares outstanding = buybacks; rising = dilution. Net debt = debt − cash (negative = net cash).

Key ratios (by fiscal year)

RatioFY2025FY2024FY2023FY2022FY2021FY2020FY2019FY2018FY2017FY2016
Operating margin-101.2%-204.0%-238.1%-757.9%-5391.9%—————
Net margin-103.6%-200.3%-238.5%-766.2%-2207.1%—————
FCF margin-61.5%-87.5%-175.9%-734.9%-4642.9%—————
Return on assets-40.9%-66.4%-55.5%-47.4%-21.1%-71.6%-45.6%-28.5%-22.2%—
Return on equity-141.3%-1199.3%-108.8%-68.5%-24.5%-80.5%-50.1%-30.1%-23.3%—
Debt / equity0.73×4.98×0.63×———————
Current ratio4.413.245.588.907.1010.1012.3819.0522.422.36

Computed from company filings · US · as of 2025-12-31. Facts plus Stocktoria's own computed scores — not investment advice.