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Septerna, Inc. SEPN

Nasdaq · stock · Pharmaceutical Preparations · website · IPO 2024-10-25

Septerna, Inc. statistics & valuation

Market cap$1.7B
P / S36.6×
P / B4.4×
P / FCF15.3×
Net margin-106.4%
Return on equity-12.8%
FCF margin238.7%
Return on capital-13.4%

Market cap as of 2026-06-29. Multiples are price-derived and refreshed daily; everything else from the latest financial reports.

Profitability & efficiency

Net margin (%)
2768.20% -6678.90% -106.40% 202320242025
Gross margin (%)
202320242025
Operating margin (%)
1374.20% -7518.40% -148.60% 202320242025
Return on equity (%)
-17.10% -12.80% 202320242025
Shares outstanding
3.2M 44.4M 44.8M 202320242025
Net debt ($)
202320242025
Share buybacks ($)
202320242025
Return on assets (%)
3.20% -15.70% -8.20% 202320242025
Free cash flow margin (%)
-27550.30% -6471.90% 238.70% 202320242025
Debt / equity (×)
202320242025
EPS ($)
$0.29 -$7.26 -$1.10 202320242025

Margins and returns computed from annual filings. Falling shares outstanding = buybacks; rising = dilution. Net debt = debt − cash (negative = net cash).

Key ratios (by fiscal year)

RatioFY2025FY2024FY2023
Operating margin-148.6%-7518.4%1374.2%
Net margin-106.4%-6678.9%2768.2%
FCF margin238.7%-6471.9%-27550.3%
Return on assets-8.2%-15.7%3.2%
Return on equity-12.8%-17.1%-10.9%
Current ratio4.7327.7716.30

Computed from company filings · US · as of 2025-12-31. Facts plus Stocktoria's own computed scores — not investment advice.