Stocktoria

Taysha Gene Therapies, Inc. TSHA

Nasdaq · stock · Biological Products, (No Diagnostic Substances) · website · IPO 2020-09-24

Taysha Gene Therapies, Inc. (TSHA) earns a Piotroski F-score of 4/9 (mixed financial health), with an Altman Z″ in the distress zone. It does not currently pay a dividend. FY2025 revenue was $9.8M at a -1115.3% net margin.

Chart by TradingView
23/100
Stocktoria Quality Score · grade D
4/9
Piotroski F — financial health
-0.53
Altman Z″ — distress risk · distress
Dividend yield · no dividend

Quality score trend · recomputed for each fiscal year

Piotroski F /9
1 1 5 3 4 20212022202320242025
Altman Z″
-4.88 -17.25 -7.40 -10.49 -0.53 20212022202320242025

Each year's score is computed from that year's filing — a rising Piotroski F or Altman Z″ means improving financial health, a fall is worth a look.

$6.41 as of 2026-08-01 · +119.3% 1y
$2.92$6.8152-wk
Market cap USD$1.8B
Net margin 5y avg-2386.1%
Return on equity 5y avg-3598.9%
Beta1.18
Employees99

Analyst price target

$12.85 +100.6% vs last
consensus: strong buy · 13 analysts
target range $10.00 – $19.00

Wall Street analyst consensus — a sentiment gauge, not our scoring.

Revenue trend · last 4y · up

How it ranks in Manufacturing · percentile among 1957 companies

Piotroski Fstronger than 45%
Net marginstronger than 10%
Return on equitystronger than 31%

Percentile vs other Manufacturing companies we cover — e.g. “stronger than 90%” means only 10% score higher on that measure.

Piotroski F breakdown · 4/9 tests passed

Altman Z″ components · distress zone

ComponentValue
Working capital / assets0.868
Retained earnings / assets-2.072
EBIT / assets-0.322
Equity / liabilities2.562

Sector peers · similar-size Manufacturing companies compare side by side →

TickerCompanyPiotroski FAltman Z″P / ERevenue growth
TSHATaysha Gene Therapies, Inc.4/9-0.53
CRISCURIS INC2/9-13.4%
ACOGAlpha Cognition Inc.2/93.69
CRBUCaribou Biosciences, Inc.2/9-9.88
ELUTELUTIA INC.4/9-8.050.8-15%
FATEFATE THERAPEUTICS INC1/9-13.3-51.2%
DBVTDBV Technologies S.A.3/9-2.63

All Manufacturing companies →

About Taysha Gene Therapies, Inc.

Taysha Gene Therapies, Inc., a clinical-stage biotechnology company, focuses on developing and commercializing adeno-associated virus-based gene therapies for the treatment of severe monogenic diseases of the central nervous system. The company primarily develops TSHA-120 for the treatment of giant axonal neuropathy; TSHA-102 for the treatment of Rett syndrome; TSHA-121 for the treatment of CLN7 disease; TSHA-118 for the treatment of CLN1 disease; TSHA-105 for the treatment of SLC13A5 deficiency; TSHA-113 for the treatment of tauopathies; TSHA-106 for the treatment of angelman syndrome; and TSHA-114 for the treatment of fragile X syndrome. The company has research, collaboration, and license agreement with The University of Texas Southwestern Medical Center. Taysha Gene Therapies, Inc. was incorporated in 2019 and is headquartered in Dallas, Texas.

FAQ

Is TSHA financially healthy?

Taysha Gene Therapies, Inc.'s Piotroski F-score is 4/9 (8–9 is excellent, 0–3 weak), and its Altman Z″ distress score is in the distress zone.

Does TSHA pay a dividend?

No, Taysha Gene Therapies, Inc. does not currently pay a dividend.

How profitable is TSHA?

In FY2025, Taysha Gene Therapies, Inc. had a net margin of -1115.3% and a return on equity of -44.1%.

What is the analyst price target for TSHA?

The average Wall-Street price target for Taysha Gene Therapies, Inc. is $12.85, about 100.6% above the recent price, from 13 analysts (consensus: strong buy).

Is TSHA a good stock to buy?

Stocktoria doesn't give buy or sell advice, but here is the data on Taysha Gene Therapies, Inc.: a Piotroski F-score of 4/9, an Altman Z″ in the distress zone. Weigh these quality and valuation signals against your own goals.

Computed from company filings · US · as of 2025-12-31. Facts plus Stocktoria's own computed scores — not investment advice.