Stocktoria
Upstream Bio, Inc. UPB
Nasdaq · XNAS · stock · Pharmaceutical Preparations · website · IPO 2024-10-11
Chart by TradingView
2/9
Piotroski F — financial health
25.63
Altman Z″ — distress risk · safe
—
Dividend payout · no dividend
Financials & ratios (annual, from 10-K)
| Metric | FY2025 | FY2024 | FY2023 |
|---|---|---|---|
| Financials | |||
| Revenue | $2.9M | $2.4M | $2.4M |
| Operating income | -$160.4M | -$77.8M | -$40.1M |
| Net income | -$143.4M | -$62.8M | -$20.5M |
| Operating cash flow | -$133.3M | -$59.2M | -$37.9M |
| Free cash flow | -$133.4M | -$59.7M | -$38.1M |
| Total assets | $353.8M | $481.7M | $117.2M |
| Total liabilities | $14.0M | $11.9M | $9.4M |
| Shareholders' equity | $339.8M | $469.9M | -$123.1M |
| Ratios | |||
| Operating margin | -5618.8% | -3281.2% | -1685.5% |
| Net margin | -5026.0% | -2650.0% | -862.9% |
| FCF margin | -4675.5% | -2518.3% | -1599.6% |
| Return on assets | -40.5% | -13.0% | -17.5% |
| Return on equity | -42.2% | -13.4% | 16.7% |
| Current ratio | 26.15 | 44.63 | 17.96 |
| Revenue growth | 20.4% | -0.4% | — |
Notable holders (13F)
| Investor | Shares | Value |
|---|---|---|
| Point72 Asset Management, L.P. | 189,668 | $1.7M |
| RENAISSANCE TECHNOLOGIES LLC | 62,100 | $558,900 |
Why these scores methodology →
Piotroski F-score: 2/9
- Positive return on assets
- Positive operating cash flow
- Rising ROA
- Cash flow exceeds net income
- Lower long-term debt
- Rising current ratio
- No share dilution
- Rising gross margin
- Rising asset turnover
Altman Z″: 25.63 (safe)
- Working capital / assets 0.956
- Retained earnings / assets -0.945
- EBIT / assets -0.453
- Equity / liabilities 24.268
Sector peers
VFS · TM · HMC · SONY · AAPL · XOM · all Manufacturing →
Source: SEC EDGAR filings · CIK 0002022626 · as of 2025-12-31. Figures are facts from filings plus Stocktoria's own computed scores — not investment advice.