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VERTEX PHARMACEUTICALS INC / MA VRTX

Nasdaq · stock · Pharmaceutical Preparations · website · IPO 1991-07-24

VERTEX PHARMACEUTICALS INC / MA statistics & valuation

Market cap$115.0B
P / E29.1×
P / S9.6×
P / B6.2×
P / FCF36.0×
Net margin32.9%
Return on equity21.2%
FCF margin26.6%
Return on capital19.2%
Graham number -70%$157.92

Market cap as of 2026-06-29. Multiples are price-derived and refreshed daily; everything else from the latest financial reports. The Graham number is Benjamin Graham's rough maximum fair value ($157.92); a green figure means the price is below it.

Profitability & efficiency

Net margin (%)
-6.60% 10.60% 68.80% 28.30% 43.70% 30.90% 37.20% 36.70% -4.90% 32.90% 2016201720182019202020212022202320242025
Gross margin (%)
2016201720182019202020212022202320242025
Operating margin (%)
0.60% 5.00% 20.80% 28.80% 46.00% 36.70% 48.20% 38.80% -2.10% 34.80% 2016201720182019202020212022202320242025
Return on equity (%)
-8.40% 12.90% 47.30% 19.30% 31.20% 23.20% 23.90% 20.60% -3.30% 21.20% 2016201720182019202020212022202320242025
Shares outstanding
248.3M 253.3M 259.2M 260.7M 263.4M 259.9M 259.1M 260.5M 257.9M 258.0M 2016201720182019202020212022202320242025
Net debt ($)
2016201720182019202020212022202320242025
Share buybacks ($)
2016201720182019202020212022202320242025
Return on assets (%)
-3.90% 7.40% 33.60% 14.10% 23.10% 17.40% 18.30% 15.90% -2.40% 15.40% 2016201720182019202020212022202320242025
Free cash flow margin (%)
10.50% 30.00% 38.50% 35.90% 48.20% 31.80% 44.00% 33.80% -7.20% 26.60% 2016201720182019202020212022202320242025
Debt / equity (×)
2016201720182019202020212022202320242025
EPS ($)
-$0.46 $1.04 $8.09 $4.51 $10.29 $9.01 $12.82 $13.89 -$2.08 $15.32 2016201720182019202020212022202320242025

Margins and returns computed from annual filings. Falling shares outstanding = buybacks; rising = dilution. Net debt = debt − cash (negative = net cash).

P / E vs its own history

VERTEX PHARMACEUTICALS INC / MA trades at about 34.3× earnings — above its 10-year norm (10-year range 22.3×–263.9×, median 30.7×).

22.3× 263.9×

Shaded band = 10-year range (22.3×–263.9×); dot = today's 34.3×.

Historical P/E = month-end price near each fiscal year-end ÷ that year's EPS. A read on whether the stock is cheap or dear relative to how it has typically been valued — not a forecast.

Key ratios (by fiscal year)

RatioFY2025FY2024FY2023FY2022FY2021FY2020FY2019FY2018FY2017FY2016
Operating margin34.8%-2.1%38.8%48.2%36.7%46.0%28.8%20.8%5.0%0.6%
Net margin32.9%-4.9%36.7%37.2%30.9%43.7%28.3%68.8%10.6%-6.6%
FCF margin26.6%-7.2%33.8%44.0%31.8%48.2%35.9%38.5%30.0%10.5%
Return on assets15.4%-2.4%15.9%18.3%17.4%23.1%14.1%33.6%7.4%-3.9%
Return on equity21.2%-3.3%20.6%23.9%23.2%31.2%19.3%47.3%12.9%-8.4%
Current ratio2.902.693.994.834.464.333.613.433.282.31

Computed from company filings · US · as of 2025-12-31. Facts plus Stocktoria's own computed scores — not investment advice.