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VYNE Therapeutics Inc. VYNE

Nasdaq · stock · Pharmaceutical Preparations · website · IPO 2018-01-25

VYNE Therapeutics Inc. statistics & valuation

Market cap$21.1M
P / S37.1×
P / B0.8×
Net margin-4646.1%
Return on equity-95.4%
Net cash$24.0M
Enterprise value USD-$2.9M
Return on capital-107.1%

Market cap as of 2026-06-29. Multiples are price-derived and refreshed daily; everything else from the latest financial reports.

Profitability & efficiency

Net margin (%)
-2087.20% -634.60% -697.00% -21484.90% -1217.40% -7876.40% -4865.80% -6710.40% -7950.90% -4646.10% 2016201720182019202020212022202320242025
Gross margin (%)
2016201720182019202020212022202320242025
Operating margin (%)
-2126.40% -645.90% -703.90% -21641.80% -1203.00% -4179.50% -7189.70% -6900.50% -8710.00% -5219.10% 2016201720182019202020212022202320242025
Return on equity (%)
-42.40% -80.50% -541.60% -681.60% -150.80% -74.40% -32.10% -76.50% -95.40% 2016201720182019202020212022202320242025
Shares outstanding
5.3M 5.3M 23.2M 9.1M 43.2M 3.0M 3.2M 14.1M 42.6M 42.8M 2016201720182019202020212022202320242025
Net debt ($)
-$11.0M -$24.4M -$42.2M -$30.9M -$30.6M -$19.9M -$24.0M 2016201720182019202020212022202320242025
Share buybacks ($)
2016201720182019202020212022202320242025
Return on assets (%)
-33.50% -43.50% -53.00% -117.30% -272.60% -109.40% -56.90% -29.10% -59.50% -87.80% 2016201720182019202020212022202320242025
Free cash flow margin (%)
-340.70% -616.50% -650.70% -16806.30% -653.50% -6054.50% 2016201720182019202020212022202320242025
Debt / equity (×)
1.86× 0.88× 0.00× 0.00× 0.00× 0.00× 0.00× 2016201720182019202020212022202320242025
EPS ($)
$7.88 -$25.64 -$7.28 -$2.78 -$0.93 -$0.62 2016201720182019202020212022202320242025

Margins and returns computed from annual filings. Falling shares outstanding = buybacks; rising = dilution. Net debt = debt − cash (negative = net cash).

Key ratios (by fiscal year)

RatioFY2025FY2024FY2023FY2022FY2021FY2020FY2019FY2018FY2017FY2016
Operating margin-5219.1%-8710.0%-6900.5%-7189.7%-4179.5%-1203.0%-21641.8%-703.9%-645.9%-2126.4%
Net margin-4646.1%-7950.9%-6710.4%-4865.8%-7876.4%-1217.4%-21484.9%-697.0%-634.6%-2087.2%
FCF margin————-6054.5%-653.5%-16806.3%-650.7%-616.5%-340.7%
Return on assets-87.8%-59.5%-29.1%-56.9%-109.4%-272.6%-117.3%-53.0%-43.5%-33.5%
Return on equity-95.4%-76.5%-32.1%-74.4%-150.8%-681.6%-541.6%-80.5%-42.4%47.8%
Debt / equity0.00×0.00×0.00×0.00×0.00×0.88×1.86×———
Current ratio12.534.3512.734.103.434.012.6114.628.178.08

Computed from company filings · US · as of 2025-12-31. Facts plus Stocktoria's own computed scores — not investment advice.